AIMC Topic: Hypoxia
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Machine learning unveils hypoxia-immune gene hub for clinical stratification of thyroid-associated ophthalmopathy.
Scientific reports
Jul 1, 2025
Thyroid-associated ophthalmopathy (TAO) is an autoimmune disorder affecting the orbit, potentially resulting in blindness. This study focused on the role of hypoxia in its pathogenesis through integrative bioinformatics and experimental validation. F...
Development and validation of a hypoxemia prediction model in middle-aged and elderly outpatients undergoing painless gastroscopy.
Scientific reports
May 23, 2025
Hypoxemia is a common complication associated with anesthesia in painless gastroscopy. With the aging of the social population, the number of cases of hypoxemia among middle-aged and elderly patients is increasing. However, tools for predicting hypox...
Intermittent hypoxemia during hemodialysis: AI-based identification of arterial oxygen saturation saw-tooth pattern.
BMC nephrology
Apr 28, 2025
BACKGROUND: Maintenance hemodialysis patients experience high morbidity and mortality, primarily from cardiovascular and infectious diseases. It was discovered recently that low arterial oxygen saturation (SaO) is associated with a pro-inflammatory p...
Exploring hypoxia driven subtypes of pulmonary arterial hypertension through transcriptomics single cell sequencing and machine learning.
Scientific reports
Apr 24, 2025
Pulmonary arterial hypertension (PAH) is a progressive cardiovascular disease characterized by elevated pulmonary arterial pressure, leading to right heart failure and death. Despite advancements in diagnosis and treatment, it remains incurable, and ...
Machine learning models compared with current clinical indices to predict the outcome of high flow nasal cannula therapy in acute hypoxemic respiratory failure.
Critical care (London, England)
Mar 7, 2025
BACKGROUND: Early identification of patients with acute hypoxemic respiratory failure (AHRF) who are at risk of failing high-flow nasal cannula (HFNC) therapy could facilitate closer monitoring, and timely adjustment/escalation of treatment. We aimed...
Exploring phenotypes to improve long-term mortality risk stratification in obstructive sleep apnea through a machine learning approach: an observational cohort study.
European journal of internal medicine
Dec 16, 2024
BACKGROUND: Obstructive sleep apnea (OSA) is a heterogeneous sleep disorder for which the identification of phenotypes might help for risk stratification for long-term mortality. Thus, the aim of the study was to identify distinct phenotypes of OSA a...
Construction and evaluation of a predictive model for the types of sleep respiratory events in patients with OSA based on hypoxic parameters.
Sleep & breathing = Schlaf & Atmung
Aug 29, 2024
OBJECTIVE: To explore the differences and associations of hypoxic parameters among distinct types of respiratory events in patients with obstructive sleep apnea (OSA) and to construct prediction models for the types of respiratory events based on hyp...
Development and experimental validation of hypoxia-related gene signatures for osteosarcoma diagnosis and prognosis based on WGCNA and machine learning.
Scientific reports
Aug 12, 2024
Osteosarcoma (OS) is the most common primary malignant tumour of the bone with high mortality. Here, we comprehensively analysed the hypoxia signalling in OS and further constructed novel hypoxia-related gene signatures for OS prediction and prognosi...
Automated glioblastoma patient classification using hypoxia levels measured through magnetic resonance images.
BMC neuroscience
May 25, 2024
INTRODUCTION: The challenge of treating Glioblastoma (GBM) tumors is due to various mechanisms that make the tumor resistant to radiation therapy. One of these mechanisms is hypoxia, and therefore, determining the level of hypoxia can improve treatme...
Role of oxygen reserve index monitoring in patients undergoing robot-assisted radical prostatectomy: a retrospective study.
World journal of urology
Apr 13, 2024
PURPOSE: Robot-assisted radical prostatectomy (RARP) is a common surgical procedure for the treatment of prostate cancer. Although beneficial, it can lead to intraoperative hypoxia due to high-pressure pneumoperitoneum and Trendelenburg position. Thi...
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