AIMC Topic: Infant

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A Machine Learning Strategy for Autism Screening in Toddlers.

Journal of developmental and behavioral pediatrics : JDBP
OBJECTIVE: Autism spectrum disorder (ASD) screening can improve prognosis via early diagnosis and intervention, but lack of time and training can deter pediatric screening. The Modified Checklist for Autism in Toddlers, Revised (M-CHAT-R) is a widely...

Fusing autonomy and sociality via embodied emergence and development of behaviour and cognition from fetal period.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences
Human-centred AI/Robotics are quickly becoming important. Their core claim is that AI systems or robots must be designed and work for the benefits of humans with no harm or uneasiness. It essentially requires the realization of autonomy, sociality an...

Predictive learning: its key role in early cognitive development.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences
What is a fundamental ability for cognitive development? Although many researchers have been addressing this question, no shared understanding has been acquired yet. We propose that predictive learning of sensorimotor signals plays a key role in earl...

A parsimonious 3-gene signature predicts clinical outcomes in an acute myeloid leukemia multicohort study.

Blood advances
Acute myeloid leukemia (AML) is a genetically heterogeneous hematological malignancy with variable responses to chemotherapy. Although recurring cytogenetic abnormalities and gene mutations are important predictors of outcome, 50% to 70% of AMLs harb...

Hematological disturbances in Down syndrome: single centre experience of thirteen years and review of the literature.

The Turkish journal of pediatrics
Karakurt N, Uslu İ, Aygün C, Albayrak C. Hematological disturbances in Down syndrome: single centre experience of thirteen years and review of the literature. Turk J Pediatr 2019; 61: 664-670. Neonates with Down syndrome (DS) may have hematological a...

Carpal Bone Segmentation Using Fully Convolutional Neural Network.

Current medical imaging reviews
BACKGROUND: Bone Age Assessment (BAA) refers to a clinical procedure that aims to identify a discrepancy between biological and chronological age of an individual by assessing the bone age growth. Currently, there are two main methods of executing BA...

A Phenotypic Description of Congenital Myotonic Dystrophy using PhenoStacks.

Journal of neuromuscular diseases
BACKGROUND: Congenital Myotonic Dystrophy (CDM1) is a rare neuromuscular condition caused by a triplet repeat expansion in the DMPK gene. Despite there being a well-recognized clinical syndrome, there has not been an effort to use a standardized onto...

Application of machine learning algorithms for the differential diagnosis of peroxisomal disorders.

Journal of biochemistry
We have established diagnostic thresholds of very long-chain fatty acids (VLCFA) for the differential diagnosis of peroxisomal disorders using the machine learning tools. The plasma samples of 131 controls and 90 cases were tested for VLCFA using gas...

Safety and Immunogenicity of Two Doses of a Quadrivalent Meningococcal Polysaccharide Diphtheria Toxoid Conjugate Vaccine in Indian and Russian Children Aged 9 to 17 Months.

Indian pediatrics
OBJECTIVE: Evaluation of tolerability, safety and immunogenicity of a two-dose series of a quadrivalent meningococcal polysaccharide diptheria toxoid conjugate (ACYW-D) vaccine in Indian and Russian infants/toddlers.