AIMC Topic: Injections, Subcutaneous

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Pharmacokinetics of single and repeat doses of icatibant.

Clinical pharmacology in drug development Feb 2, 2015
PURPOSE: Icatibant is a bradykinin-2 receptor antagonist approved to treat acute hereditary angioedema attacks in adults. To-date, no thorough investigation of the clinical pharmacokinetic (PK) parameters of icatibant and its primary metabolites has ...
Bradykinin B2 Receptor Antagonists Bradykinin Adult Male Middle Aged Adolescent Female Young Adult Humans Healthy Volunteers Half-Life Drug Administration Schedule Area Under Curve Injections, Subcutaneous Metabolic Clearance Rate Models, Biological Anti-Inflammatory Agents, Non-Steroidal
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Predicting Secukinumab Fast-Responder Profile in Psoriatic Patients: Advanced Application of Artificial-Neural-Networks (ANNs).

Journal of drugs in dermatology : JDD Dec 1, 2020
BACKGROUND: Drug resistance to biologics in psoriasis therapy can occur – it may be acquired during a treatment or else present itself from the beginning. To date, no biomarkers are known that may reliably guide clinicians in predicting respons...
Humans Prognosis Female Prospective Studies Biomarkers Antibodies, Monoclonal, Humanized Psoriasis Injections, Subcutaneous Treatment Outcome Drug Resistance Models, Immunological Severity of Illness Index Biological Products Predictive Value of Tests Deep Learning Pilot Projects Time Factors Adult Male Middle Aged
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Use of Artificial Intelligence to Improve Diabetes Outcomes in Patients Using Multiple Daily Injections Therapy.

Diabetes technology & therapeutics Jun 1, 2019
Biomedical Technology Glycated Hemoglobin Artificial Intelligence Injections, Subcutaneous Diabetes Mellitus, Type 1 Hypoglycemic Agents Humans
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Antiphospholipid Syndrome with Antiβ2glicoprotein-1 Antibodies as the Cause of Recurrent Tibial Vein Thrombosis in SAPHO syndrome.

Acta dermatovenerologica Croatica : ADC Dec 1, 2016
The antiphospholipid antibody syndrome is defined by the presence of antiphospholipid antibodies in patients with recurrent venous or arterial thromboembolism (1). SAPHO syndrome is a rare disease, characterized by specific clinical manifestations of...
Enoxaparin Antiphospholipid Syndrome Risk Assessment Recurrence Rare Diseases Ultrasonography Female Injections, Subcutaneous Acquired Hyperostosis Syndrome Adult Venous Thrombosis Follow-Up Studies Antibodies, Anticardiolipin Humans
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