AIMC Topic: Insulin Resistance
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Evaluation of insulin sensitivity temporal prediction by using quantile regression combined with neural network model.
International journal of medical informatics
Oct 1, 2025
BACKGROUND: Stress-induced hyperglycemia, a pathologically high blood glucose level, is a frequent complication in intensive care units. Blood glucose (BG) level control is crucial but challenging due to patient variability. The Stochastic TARgeted (...
Prediction Model for Insulin Resistance and Implications for MASLD in Youth: A Novel Marker, the Pediatric Insulin Resistance Assessment Score.
Yonsei medical journal
Aug 1, 2025
PURPOSE: Insulin resistance (IR) is a condition closely associated with cardiovascular risk factors and metabolic dysfunction-associated steatotic liver disease (MASLD) is emerging as a significant IR-related complication. We aimed to develop a predi...
Prediction of Insulin Resistance in Nondiabetic Population Using LightGBM and Cohort Validation of Its Clinical Value: Cross-Sectional and Retrospective Cohort Study.
JMIR medical informatics
Jun 13, 2025
BACKGROUND: Insulin resistance (IR), a precursor to type 2 diabetes and a major risk factor for various chronic diseases, is becoming increasingly prevalent in China due to population aging and unhealthy lifestyles. Current methods like the gold-stan...
Exploring the effect of the triglyceride-glucose index on bone metabolism in prepubertal children, a retrospective study: insights from traditional methods and machine-learning-based bone remodeling prediction.
PeerJ
Jan 1, 2025
BACKGROUND: Childhood obesity poses a significant risk to bone health, but the impact of insulin resistance (IR) on bone metabolism in prepubertal children, as assessed by the triglyceride-glucose (TyG) index, remains underexplored. Bone turnover mar...
Machine learning-based clustering identifies obesity subgroups with differential multi-omics profiles and metabolic patterns.
Obesity (Silver Spring, Md.)
Nov 1, 2024
OBJECTIVE: Individuals living with obesity are differentially susceptible to cardiometabolic diseases. We hypothesized that an integrative multi-omics approach might improve identification of subgroups of individuals with obesity who have distinct ca...
Relationship of the low-density lipoprotein (LDL)/high-density lipoprotein (HDL) index with antioxidant enzymes and with the oxLDL/HDL index.
Gaceta medica de Mexico
Jan 1, 2019
INTRODUCTION: The low-density lipoprotein (LDL)/high-density lipoprotein (HDL) index is a predictive factor for atherosclerosis, which is associated with oxidative modifications.
[Antidiabetic role of high density lipoproteins].
Biomeditsinskaia khimiia
Nov 1, 2018
Disturbance in lipid metabolism can be both a cause and a consequence of the development of diabetes mellitus (DM). One of the most informative indicator of lipid metabolism is the ratio of atherogenic and antiatherogenic fractions of lipoproteins an...
Thyroid disorders in obese patients. Does insulin resistance make a difference?
Archives of endocrinology and metabolism
Dec 1, 2017
OBJECTIVE: The aim of this study was to evaluate the association between insulin resistance and thyroid pathology in obese patients, and compare the results between insulin-resistant and noninsulin-resistant patients.
Estimating glucose requirements of an activated immune system in growing pigs.
Journal of animal science
Nov 1, 2017
Activated immune cells become obligate glucose utilizers, and a large i.v. lipopolysaccharide (LPS) dose causes insulin resistance and severe hypoglycemia. Therefore, study objectives were to quantify the amount of glucose needed to maintain euglycem...
Adiponectin levels may help assess the clinical repercussions of obesity irrespective of body mass index.
Hormones (Athens, Greece)
Jul 1, 2017
OBJECTIVE: Adiponectin is the major product of adipose tissue. The aim of this study was to associate adiponectin levels with adipose tissue and metabolic indices.
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