AIMC Topic: Knowledge Bases

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TaggerOne: joint named entity recognition and normalization with semi-Markov Models.

Bioinformatics (Oxford, England) Jun 9, 2016
MOTIVATION: Text mining is increasingly used to manage the accelerating pace of the biomedical literature. Many text mining applications depend on accurate named entity recognition (NER) and normalization (grounding). While high performing machine le...
Machine Learning Software Pattern Recognition, Automated Data Mining Terminology as Topic Information Storage and Retrieval Disease Semantics Forecasting Computational Biology Knowledge Bases
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A knowledge-based approach for predicting gene-disease associations.

Bioinformatics (Oxford, England) Jun 9, 2016
MOTIVATION: Recent advances of next-generation sequence technologies have made it possible to rapidly and inexpensively identify gene variations. Knowing the disease association of these gene variations is important for early intervention to treat de...
Regression Analysis Knowledge Bases Gene Expression Profiling Disease Protein Interaction Mapping Humans Genome-Wide Association Study Gene Regulatory Networks Epistasis, Genetic Algorithms Models, Genetic Databases, Genetic
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Evaluation of knowledge-based reconstruction for magnetic resonance volumetry of the right ventricle after arterial switch operation for dextro-transposition of the great arteries.

The international journal of cardiovascular imaging Jun 2, 2016
Right ventricular (RV) volume and function evaluation is essential in the follow-up of patients after arterial switch operation (ASO) for dextro-transposition of the great arteries (d-TGA). Cardiac magnetic resonance (CMR) imaging using the Simpson's...
Knowledge Bases Image Interpretation, Computer-Assisted Observer Variation Feasibility Studies Ventricular Dysfunction, Right Heart Ventricles Hypertrophy, Right Ventricular Ventricular Function, Right Transposition of Great Vessels Magnetic Resonance Imaging, Cine Arterial Switch Operation Adolescent Time Factors Ontario Treatment Outcome Predictive Value of Tests Female Anatomic Landmarks Reproducibility of Results Male Humans Retrospective Studies
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The BioHub Knowledge Base: Ontology and Repository for Sustainable Biosourcing.

Journal of biomedical semantics Jun 1, 2016
BACKGROUND: The motivation for the BioHub project is to create an Integrated Knowledge Management System (IKMS) that will enable chemists to source ingredients from bio-renewables, rather than from non-sustainable sources such as fossil oil and its d...
Knowledge Bases Semantics Conservation of Natural Resources Chemical Engineering Internet
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DIY-Bio - economic, epistemological and ethical implications and ambivalences.

Life sciences, society and policy May 30, 2016
Since 2008, we witness the emergence of the Do-It-Yourself Biology movement, a global movement spreading the use of biotechnology beyond traditional academic and industrial institutions and into the lay public. Practitioners include a broad mix of am...
Synthetic Biology Humans Biomedical Research Ethics, Research Knowledge Bases United States Europe
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The Knowledge Base for Achieving the Sustainable Development Goal Targets on Water Supply, Sanitation and Hygiene.

International journal of environmental research and public health May 27, 2016
Safe drinking water, sanitation, and hygiene (WASH) are fundamental to an improved standard of living. Globally, 91% of households used improved drinking water sources in 2015, while for improved sanitation it is 68%. Wealth disparities are stark, wi...
Hygiene Conservation of Natural Resources Sanitation Water Supply Humans Knowledge Bases Climate Change
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Collective intelligence in medical diagnosis systems: A case study.

Computers in biology and medicine Apr 29, 2016
Diagnosing a patient's condition is one of the most important and challenging tasks in medicine. We present a study of the application of collective intelligence in medical diagnosis by applying consensus methods. We compared the accuracy obtained wi...
Humans Diagnosis, Computer-Assisted Knowledge Bases Biological Ontologies
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DiMeX: A Text Mining System for Mutation-Disease Association Extraction.

PloS one Apr 13, 2016
The number of published articles describing associations between mutations and diseases is increasing at a fast pace. There is a pressing need to gather such mutation-disease associations into public knowledge bases, but manual curation slows down th...
Knowledge Bases Databases, Genetic Humans Data Mining Natural Language Processing Genetic Predisposition to Disease Mutation Computational Biology
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A Knowledge-Based System for Display and Prediction of O-Glycosylation Network Behaviour in Response to Enzyme Knockouts.

PLoS computational biology Apr 7, 2016
O-linked glycosylation is an important post-translational modification of mucin-type protein, changes to which are important biomarkers of cancer. For this study of the enzymes of O-glycosylation, we developed a shorthand notation for representing Ga...
Polysaccharides Knowledge Bases Mucins Glycosyltransferases Genetic Engineering Terminology as Topic Gene Knockout Techniques Cricetulus Metabolic Networks and Pathways Models, Biological Glycosylation Protein Processing, Post-Translational CHO Cells Humans Animals Computer Simulation Computational Biology
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RegenBase: a knowledge base of spinal cord injury biology for translational research.

Database : the journal of biological databases and curation Apr 7, 2016
Spinal cord injury (SCI) research is a data-rich field that aims to identify the biological mechanisms resulting in loss of function and mobility after SCI, as well as develop therapies that promote recovery after injury. SCI experimental methods, da...
Knowledge Bases Spinal Cord Injuries Humans Rats Disease Models, Animal Databases, Factual Translational Research, Biomedical Animals Mice
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