Silver nanoclusters and graphene oxide nanocomposite (AgNCs/GRO) is synthesized and functionalized with detection antibody for highly sensitive electrochemical sensing of carcinoembryonic antigen (CEA), a model tumor marker involved in many cancers. ...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Dec 5, 2014
Spectrophotometric analysis method based on the combination of the principal component analysis (PCA) with the feed-forward neural network (FFNN) and the radial basis function network (RBFN) was proposed for the simultaneous determination of paraceta...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Dec 15, 2025
Accurate and sensitive detection of small-molecule metabolites such as uric acid, glucose, and lactic acid is critical in biomedical diagnostics and clinical applications. Traditional detection methods often face limitations such as complex procedure...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Nov 5, 2025
Due to the inherent specificity and high sensitivity, biomedical detections based on Surface-Enhanced Raman Scattering (SERS) technology have garnered increasing attention. In the SERS detection process, fabricating a highly sensitive SERS substrate ...
A dual-mode approach was developed for dopamine (DA) assay based on boron (B) and nitrogen (N) co-doped carbon dots (B, N-CDs). This platform enabled highly sensitive and specific detection of DA in biological samples through collaborative ratio fluo...
Surface plasmon resonance (SPR) enables in situ, label-free, real-time molecular detection. However, traditional SPR biosensors require complex and precise large-scale equipment, with detection limits constrained by multiple factors, complicating and...
The increasing demand for point-of-care detection of low-concentration cancer biomarkers has necessitated the development of innovative nanozyme-based sensing technologies. Here, a smartphone-integrated platform is presented that utilizes artificial ...
The shortage in early detection methods for the pathogen Burkholderia gladioli pv. cocovenenans (BGC) and its toxin bongkrekic acid rises the risk for food poisoning. Combining Headspace-Gas Chromatography-Ion Mobility Spectrometry (HS-GC-IMS) with c...
Glutathione (GSH) levels have been linked to aging and the pathogenesis of various diseases, highlighting the necessity for the development of sensitive analytical methods for GSH to facilitate disease diagnosis and treatment. In this study, we synth...
The ideal multifunctional platform that combines the capabilities of effective capture, sensitive detection, and accurate identification of doxycycline analogs (DCs) remains a serious challenge for ensuring the environment and food security. This wor...
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