AIMC Topic: Lymphatic Metastasis

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Automated contouring of gross tumor volume lymph nodes in lung cancer by deep learning.

BMC cancer
PURPOSE: The precise contouring of gross tumor volume lymph nodes (GTVnd) is an essential step in clinical target volume delineation. This study aims to propose and evaluate a deep learning model for segmenting GTVnd specifically in lung cancer, repr...

Historical evolution and current research status of lymph node staging in gastric cancer: a review.

World journal of surgical oncology
Lymph node metastasis (LNM) is an independent prognostic factor for patients with gastric cancer (GC), and an accurate lymph node (LN) staging system is crucial for guiding adjuvant therapy and assessing patient prognosis. The most commonly used stag...

Immune subtyping of lymph node metastasis-negative colorectal cancer reveals biomarkers for prognosis and immunotherapy response.

PloS one
BACKGROUND: Lymph node metastasis (LNM) is a key prognostic factor in colorectal cancer (CRC), and early lymph node status assessment is crucial for prognosis and immunotherapy decisions. However, the immune characteristics of LNM-negative CRC remain...

Predicting Lymph Node Metastasis in Rectal Cancer: Development and Validation of a Machine Learning Model Using Clinical Data.

JMIR medical informatics
BACKGROUND: Rectal cancer (RC) is a common malignant tumor, with lymph node metastasis (LNM) being a critical determinant of patient prognosis. Traditional diagnostic methods have limitations, necessitating the development of predictive models using ...

Micrometastasis and Isolated Tumor Cells in Oral Squamous Cell Carcinoma: Refining Nodal Staging with Emerging Technologies.

Head and neck pathology
PURPOSE: Cervical lymph node metastasis significantly influence prognosis in oral squamous cell carcinoma (OSCC), guiding staging, treatment decisions, and overall survival. Sentinel lymph node biopsy (SLNB) offers a minimally invasive approach for e...

CT-based machine learning model integrating intra- and peri-tumoral radiomics features for predicting occult lymph node metastasis in peripheral lung cancer.

Cancer imaging : the official publication of the International Cancer Imaging Society
BACKGROUND: Accurate preoperative assessment of occult lymph node metastasis (OLNM) plays a crucial role in informing therapeutic decision-making for lung cancer patients. Computed tomography (CT) is the most widely used imaging modality for preopera...

An explainable predictive machine learning model for axillary lymph node metastasis in breast cancer based on multimodal data: A retrospective single-center study.

Journal of translational medicine
OBJECTIVE: To develop explainable machine learning models that integrate multimodal imaging and pathological biomarkers to predict axillary lymph node metastasis (ALNM) in breast cancer patients and assess their clinical utility.

Prediction of cervical cancer lymph node metastasis based on multisequence magnetic resonance imaging radiomics and deep learning features: a dual-center study.

Scientific reports
Cervical cancer is a leading cause of death from malignant tumors in women, and accurate evaluation of occult lymph node metastasis (OLNM) is crucial for optimal treatment. This study aimed to develop several predictive models-including Clinical mode...

Ultrasound derived deep learning features for predicting axillary lymph node metastasis in breast cancer using graph convolutional networks in a multicenter study.

Scientific reports
The purpose of this study was to create and validate an ultrasound-based graph convolutional network (US-based GCN) model for the prediction of axillary lymph node metastasis (ALNM) in patients with breast cancer. A total of 820 eligible patients wit...

Establishment of an interpretable MRI radiomics-based machine learning model capable of predicting axillary lymph node metastasis in invasive breast cancer.

Scientific reports
This study sought to develop a radiomics model capable of predicting axillary lymph node metastasis (ALNM) in patients with invasive breast cancer (IBC) based on dual-sequence magnetic resonance imaging(MRI) of diffusion-weighted imaging (DWI) and dy...