BACKGROUND: Renal cell carcinoma (RCC) is a prevalent malignancy with highly variable outcomes. MicroRNA-15a (miR-15a) has emerged as a promising prognostic biomarker in RCC, linked to angiogenesis, apoptosis, and proliferation. Radiogenomics integra...
The pupillary response is a valuable indicator of cognitive workload, capturing fluctuations in attention and arousal governed by the autonomic nervous system. Cognitive events, defined as the initiation of mental processes, are closely linked to cog...
We combine daily internet search data and monthly information on medical expenditures for anti-depressants to test two distinct hypotheses in eight Australian states, covering the period from 2020 to 2022. First, whether using daily search data can h...
Journal of orthopaedic surgery and research
Aug 20, 2025
BACKGROUND: Identifying patients unlikely to achieve meaningful improvement following total knee arthroplasty (TKA) supports more effective shared decision-making (SDM). This study aimed to develop and validate machine learning (ML) models that preop...
The prompt diagnosis of pulmonary infections with unknown etiology in patients in severe condition remains a challenge due to the lack of rapid and effective diagnostic methods. While metatranscriptomic sequencing offers a powerful approach, its clin...
Hepatitis continues to be a major global health challenge, leading to high morbidity and mortality rates. Despite advances in diagnosis and treatment, early prediction of hepatitis outcomes remains an essential area for improvement. This study seeks ...
Phytoplankton-derived dissolved organic carbon (DOC) is a major pathway for atmospheric CO transfer to long-lived oceanic DOC reservoirs. Yet, current models rarely accounted for its molecular and taxonomic heterogeneity across growth seasons. Here, ...
Adolescent Self-Injurious Behavior (SIB) is a significant global public health issue, with a lifetime prevalence rate of approximately 13.7%. As awareness of SIB rises, there is an urgent need for effective prediction mechanisms to enable early ident...
The intricate landscape of tRNA modification presents persistent analytical challenges, which have impeded efforts to simultaneously resolve sequence, modification, and aminoacylation state at the level of individual tRNAs. To address these challenge...
Variations in host species significantly impact bacterial growth traits and antibiotic resistance, making it essential to consider host origin when evaluating the zoonotic potential of pathogens. This study focuses on multiple Brucella species, which...
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