Recent research in DNA nanotechnology has demonstrated that biological substrates can be used for computing at a molecular level. However, in vitro demonstrations of DNA computations use preprogrammed, rule-based methods which lack the adaptability t...
Journal of infection and public health
Apr 10, 2019
BACKGROUND: Middle East Respiratory Syndrome (MERS) is a major infectious disease which has affected the Middle Eastern countries, especially the Kingdom of Saudi Arabia (KSA) since 2012. The high mortality rate associated with this disease has been ...
OBJECTIVE: Machine learning techniques have demonstrated superior discrimination compared to conventional statistical approaches in predicting trauma death. The objective of this study is to evaluate whether machine learning algorithms can be used to...
IEEE/ACM transactions on computational biology and bioinformatics
Apr 9, 2019
Synthetic lethality (SL) is a promising concept for novel discovery of anti-cancer drug targets. However, wet-lab experiments for detecting SLs are faced with various challenges, such as high cost, low consistency across platforms, or cell lines. The...
Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation
Apr 9, 2019
OBJECTIVES: Survival after liver transplant depends on pretransplant, peritransplant, and posttransplant factors. Identifying effective factors for patient survival after transplant can help transplant centers make better decisions.
Saponins are a type of compounds bearing a hydrophobic steroid/triterpenoid moiety and hydrophilic carbohydrate branches. The majority of the saponins demonstrate a broad range of prominent pharmacological activities. Nevertheless, many saponins also...
The European Medicines Agency has defined Big Data by the "3 V's": Volume, Velocity and Variety. These large databases allow access to real life data on patient care. They are particularly suited for studies of adverse events and pharmacoepidemiology...
International journal of computer assisted radiology and surgery
Apr 9, 2019
PURPOSE: For many applications in the field of computer-assisted surgery, such as providing the position of a tumor, specifying the most probable tool required next by the surgeon or determining the remaining duration of surgery, methods for surgical...
IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
Apr 9, 2019
Powered intelligent lower limb prosthesis can actuate the knee and ankle joints, allowing transfemoral amputees to perform seamless transitions between locomotion states with the help of an intent recognition system. However, prior intent recognition...
BMC medical informatics and decision making
Apr 9, 2019
BACKGROUND: Reinforcement learning (RL) provides a promising technique to solve complex sequential decision making problems in health care domains. However, existing studies simply apply naive RL algorithms in discovering optimal treatment strategies...
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