AIMC Topic: Machine Learning

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Application of Machine-Learning Models to Predict Tacrolimus Stable Dose in Renal Transplant Recipients.

Scientific reports
Tacrolimus has a narrow therapeutic window and considerable variability in clinical use. Our goal was to compare the performance of multiple linear regression (MLR) and eight machine learning techniques in pharmacogenetic algorithm-based prediction o...

In-lab versus at-home activity recognition in ambulatory subjects with incomplete spinal cord injury.

Journal of neuroengineering and rehabilitation
BACKGROUND: Although commercially available activity trackers can aid in tracking therapy and recovery of patients, most devices perform poorly for patients with irregular movement patterns. Standard machine learning techniques can be applied on reco...

A machine learning classifier trained on cancer transcriptomes detects NF1 inactivation signal in glioblastoma.

BMC genomics
BACKGROUND: We have identified molecules that exhibit synthetic lethality in cells with loss of the neurofibromin 1 (NF1) tumor suppressor gene. However, recognizing tumors that have inactivation of the NF1 tumor suppressor function is challenging be...

Multi-Instance Metric Transfer Learning for Genome-Wide Protein Function Prediction.

Scientific reports
Multi-Instance (MI) learning has been proven to be effective for the genome-wide protein function prediction problems where each training example is associated with multiple instances. Many studies in this literature attempted to find an appropriate ...

Ontology-based automatic identification of public health-related Turkish tweets.

Computers in biology and medicine
Social media analysis, such as the analysis of tweets, is a promising research topic for tracking public health concerns including epidemics. In this paper, we present an ontology-based approach to automatically identify public health-related Turkish...

Gradient Boosted Decision Tree Classification of Endophthalmitis Versus Uveitis and Lymphoma from Aqueous and Vitreous IL-6 and IL-10 Levels.

Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics
PURPOSE: To investigate the effectiveness of gradient boosting to classify endophthalmitis versus uveitis and lymphoma by intraocular cytokine levels.

Predicting DPP-IV inhibitors with machine learning approaches.

Journal of computer-aided molecular design
Dipeptidyl peptidase IV (DPP-IV) is a promising Type 2 diabetes mellitus (T2DM) drug target. DPP-IV inhibitors prolong the action of glucagon-like peptide-1 (GLP-1) and gastric inhibitory peptide (GIP), improve glucose homeostasis without weight gain...

Machine Learning Will Change Medicine.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Predicting human behavior: The next frontiers.

Science (New York, N.Y.)
Machine learning has provided researchers with new tools for understanding human behavior. In this article, we briefly describe some successes in predicting behaviors and describe the challenges over the next few years.