AIMC Topic: Machine Learning

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A Neighbor-Sensitive Multi-Modal Flexible Learning Framework for Improved Prostate Tumor Segmentation in Anisotropic MR Images.

IEEE transactions on bio-medical engineering
Accurate segmentation of prostate tumors from multi-modal magnetic resonance (MR) images is crucial for the diagnosis and treatment of prostate cancer. However, the robustness of existing segmentation methods is limited, mainly because these methods ...

Risk Prediction of Low Bone Density in Elderly Patients with Supervised Machine Learning Algorithms.

Balkan medical journal
BACKGROUND: Low bone mineral density (BMD) is a common age-related condition that elevates the risk of fractures and mortality. Machine learning (ML) techniques offer a promising approach for early prediction using readily available clinical, biochem...

Interplay of PRMTs and Identification of Biomarkers Through Machine Learning Algorithms in Pan-Cancer, Highlighting PRMT3 as a Biomarker in Pancreatic Cancer.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Protein arginine methylation was a common post-translational modification, playing a key role in many biological processes and disease. But the regulatory mechanisms of protein arginine methyltransferases (PRMTs) in cancer were not well understood. T...

Robustness of steroidomics-based machine learning for diagnosis of primary aldosteronism: a laboratory medicine perspective.

Clinical chemistry and laboratory medicine
OBJECTIVES: Use of machine learning (ML) in diagnostics offers promise to optimise interpretation of laboratory data and guide clinical decision-making. For this, ML-based outputs should provide robustly reproducible results at least as good as the u...

Machine learning reveal shared diagnostic biomarkers and convergent pathways in age-related hearing loss and sarcopenia.

Medicine
Age-related hearing loss (HL) and sarcopenia (ARS) are prevalent geriatric syndromes sharing common risk factors. This study aimed to identify shared biomarkers and elucidate convergent pathogenic mechanisms. Transcriptomic datasets were obtained fro...

Identification of key genes in cuproptosis during acute kidney injury through weighted gene co-expression network analysis.

Medicine
Acute kidney injury (AKI) is a serious condition characterized by a rapid decline in renal function, leading to severe complications. Recent findings suggest that cuproptosis-related genes (CuRGs) influence AKI mechanisms. This study investigated CuR...

Machine learning prediction of thrombolysis efficacy using hs-CRP and inflammatory markers in stroke.

Medicine
The aim of this study was to investigate the relationship between serum ultrasensitive C-reactive protein (hs-CRP) levels and stroke incidence and to assess its potential role in decision-making for thrombolytic therapy in stroke. Given that hs-CRP i...

Identification and validation of feature genes in hepatocellular carcinoma based on bioinformatics and machine learning: An observational study.

Medicine
The incidence of hepatocellular carcinoma (HCC) has risen significantly in recent years, while current diagnostic and therapeutic approaches remain suboptimal. This study aimed to identify novel biomarkers and therapeutic targets to improve early det...

Integrated bioinformatics analysis and machine learning identifies FZD4, SRPX2, and COL8A1 as angiogenesis hub genes in endometriosis.

Medicine
This study aims to identify angiogenesis-associated genes (AAGs) in endometriosis (EM) by integrating bioinformatics analysis with machine learning, and to investigate their underlying mechanisms. Differentially expressed genes (DEGs) were screened f...

Prediction of mortality in cancer patients with COVID-19 using machine learning methods.

Medicine
This study aimed to predict mortality in cancer patients diagnosed with COVID-19 using machine learning (ML) algorithms and identify the clinical and laboratory parameters associated with mortality. Demographic, clinical, and laboratory data of cance...