BACKGROUND: Despite advances in pain management, inadequate pain relief and opioid-related adverse events remain common challenges in perioperative care, often contributing to prolonged recovery and reduced quality of life. The perioperative opioid a...
Protein science : a publication of the Protein Society
Jul 1, 2025
Accurate prediction of protein function is fundamental to understanding biological processes, with computational methods becoming increasingly essential as experimental methods struggle to keep pace with the rate of newly discovered proteins. Despite...
Infectious diseases, a major contributor to high mortality rates, often exhibit similar symptoms, despite variations in immune responses to bacterial or viral infections. Rapidly differentiating bacterial infections from viral infections in febrile p...
Metabolic-associated fatty liver disease (MAFLD), a global health challenge linked to metabolic syndrome, requires accurate severity stratification for clinical management. Current invasive diagnostic methods limit practical implementation. This stud...
Protein science : a publication of the Protein Society
Jul 1, 2025
Many antimicrobial peptides (AMPs) function by disrupting the cell membranes of microbes. While this ability is crucial for their efficacy, it also raises questions about their safety. Specifically, the membrane-disrupting ability could lead to hemol...
Emerging pollutants such as tetracycline antibiotics (TCs) have garnered attention due to their ecological impacts and the evolution of drug resistance. However, the comprehensive monitoring of TCs remains inadequate. This study presents a multifunct...
Artificial intelligence (AI) encompasses a variety of computer algorithms that have a wide range of potential clinical applications in nuclear cardiology. This article will introduce core terminology and concepts for AI including classifications of A...
Journal of the American Medical Informatics Association : JAMIA
Jul 1, 2025
OBJECTIVE: Machine learning algorithms can advance clinical care, including identifying mental health conditions. These algorithms are often developed without considering the perspectives of the affected populations. This study describes the process ...
Many members of the broad family of enzymes, known as YcaOs have been shown to install azoline heterocycles post-translationally into peptide substrates. These moieties can help rigidify structures and contribute to the potent bioactivities of the ev...
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