BACKGROUND AND PURPOSE: Glioblastoma (GBM), the most frequent and aggressive brain tumour in adults, is associated with a dismal prognostic despite intensive treatment involving surgery, radiotherapy and temozolomide (TMZ)-based chemotherapy. The ini...
The journal of trauma and acute care surgery
Apr 14, 2025
BACKGROUND: The Rib Fracture Frailty (RFF) Index is an internally validated machine learning-based risk assessment tool for adult patients with rib fractures that requires minimal provider entry. Existing frailty risk scores have yet to undergo head-...
PURPOSE: Fluorescence imaging is critical for intraoperative intestinal perfusion assessment in colorectal surgery, yet its clinical adoption remains limited by subjective interpretation and lack of quantitative standards. This study introduces an in...
Journal of chemical information and modeling
Apr 14, 2025
Recently, therapeutic peptides have demonstrated great promise for cancer treatment. To explore powerful anticancer peptides, artificial intelligence (AI)-based approaches have been developed to systematically screen potential candidates. However, th...
Journal of chemical information and modeling
Apr 14, 2025
Missense mutations in oncogenic proteins that are concurrently associated with neurodevelopmental disorders have garnered significant attention. Phosphatase and tensin homologue (PTEN) serves as a paradigmatic model for mapping its mutational landsca...
The marine environment is grappling with microplastic (MP) pollution, necessitating an understanding of its distribution patterns, influencing factors, and potential ecological risks. However, the vast area of the ocean and budgetary constraints make...
Newcastle disease virus (NDV) continues to present a significant challenge for vaccination due to its rapid evolution and the emergence of new variants. Although molecular and sequence data are now quickly and inexpensively produced, genetic distance...
: The microbiome plays an important role in cancer, but the relationship between dietary habits and the microbiota in oesophageal squamous cell carcinoma (ESCC) is not clear. The aim of this study is to explore the complex relationship between the mi...
BACKGROUND: Early identification of Schizophrenia Spectrum Disorder (SSD) is crucial for effective intervention and prognosis improvement. Previous neuroimaging-based classifications have primarily focused on chronic, medicated SSD cohorts. However, ...
BACKGROUND: The relationship between cytokines and lung metastasis (LM) in breast cancer (BC) remains unclear and current clinical methods for identifying breast cancer lung metastasis (BCLM) lack precision, thus underscoring the need for an accurate...
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.