Thyroid hormones control crucial physiological activities, such as metabolism, oxidative stress, erythropoiesis, thermoregulation, and organ development. Hormonal imbalances may cause serious conditions like cognitive impairment, depression, and nerv...
The prevalence of Leukaemia, a malignant blood cancer that originates from hematopoietic progenitor cells, is increasing in Southeast Asia, with a worrisome fatality rate of 54%. Predicting outcomes in the early stages is vital for improving the chan...
With growing uncertainty in global trade, improving access to domestic capital markets has become an important way to manage financial risk spillovers. This study examines how the registration system reform affects the finance sector's risk spillover...
Academic achievement is an important index to measure the quality of education and students' learning outcomes. Reasonable and accurate prediction of academic achievement can help improve teachers' educational methods. And it also provides correspond...
Journal of chemical information and modeling
Jun 17, 2025
Accurate prediction of drug-protein interactions is crucial for drug discovery. Due to the bottleneck of traditional scoring functions, many machine learning scoring functions (MLSFs) have been proposed for structure-based drug screening. However, ex...
Journal of chemical information and modeling
Jun 17, 2025
We demonstrate the usefulness of general atom- and bond-level density functional theory (DFT) descriptors to enhance the performance of neural networks for general reaction condition prediction. We treat condition prediction as a multiclass classific...
OBJECTIVES: Unplanned pneumonia readmissions increase patient morbidity, mortality and healthcare costs. Among pneumonia patients, the middle-aged and elderly (≥45 years old) have a significantly higher risk of readmission compared with the young. Gi...
Journal of cancer research and clinical oncology
Jun 17, 2025
BACKGROUND: With the improvement of imaging, the screening rate of Pulmonary nodules (PNs) has further increased, but their identification of High-Risk Prognostic Pathological Components (HRPPC) is still a major challenge. In this study, we aimed to ...
Biomolecular force fields have continuously evolved to improve their accuracy and broaden their applications in biological and therapeutic discoveries. The rapid adaptation of advanced computational technology, in particular the recent deep learning ...
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