Journal of chemical information and modeling
Mar 12, 2025
The goal of drug repositioning is to expedite the drug development process by finding novel therapeutic applications for approved drugs. Using multifeature learning, different computational drug repositioning techniques have recently been introduced ...
Optimizing enzymes to function in novel chemical environments is a central goal of synthetic biology, but optimization is often hindered by a rugged fitness landscape and costly experiments. In this work, we present TeleProt, a machine learning (ML) ...
There is great interest in using genetically tractable organisms such as to gain insights into the regulation and function of sleep. However, sleep phenotyping in has largely relied on simple measures of locomotor inactivity. Here, we present FlyVI...
Model-agnostic meta-learning (MAML), coupled with digital twins, is transformative for predictive maintenance (PdM), especially in robotic arms in assembly lines, where rapid and accurate fault classification of arms is essential. Despite gaining sig...
International journal of molecular sciences
Mar 12, 2025
Chronic myeloid leukemia is a clonal hematologic disease characterized by the presence of the Philadelphia chromosome and the BCR::ABL1 fusion protein. Integrating different molecular, genetic, clinical, and laboratory data would improve the diagnost...
Cancer imaging : the official publication of the International Cancer Imaging Society
Mar 12, 2025
PURPOSE: This study aimed to select robust features against lung motion in a phantom study and use them as input to feature selection algorithms and machine learning classifiers in a clinical study to predict the lymphovascular invasion (LVI) of non-...
Cancer imaging : the official publication of the International Cancer Imaging Society
Mar 12, 2025
BACKGROUND: Programmed death ligand 1 (PD-L1) expression status, closely related to immunotherapy outcomes, is a reliable biomarker for screening patients who may benefit from immunotherapy. Here, we developed and validated an interpretable machine l...
BACKGROUND: Vaccine hesitancy, the delay in acceptance or reluctance to vaccinate, ranks among the top threats to global health. Identifying modifiable factors contributing to vaccine hesitancy is crucial for developing targeted interventions to incr...
OBJECTIVE: Predicting healthcare demand is essential for effective resource allocation and planning. This study applies Andersen's Behavioral Model of Health Services Use, focusing on predisposing, enabling, and need factors, using data from the 2022...
The evolution experienced by global society, in the post-COVID 19 era, is marked by the quite obligatory use of digital media in many sectors, as is the case for the health sector. Quite frequently, both patients and health professionals use social m...
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