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Computer aided diagnosis for suspect keratoconus detection.

Computers in biology and medicine
PURPOSE: To develop a stable and low-cost computer aided diagnosis (CAD) system for early keratoconus detection for clinical use.

Spiking Neural Network Modelling Approach Reveals How Mindfulness Training Rewires the Brain.

Scientific reports
There has been substantial interest in Mindfulness Training (MT) to understand how it can benefit healthy individuals as well as people with a broad range of health conditions. Research has begun to delineate associated changes in brain function. How...

Deep convolutional models improve predictions of macaque V1 responses to natural images.

PLoS computational biology
Despite great efforts over several decades, our best models of primary visual cortex (V1) still predict spiking activity quite poorly when probed with natural stimuli, highlighting our limited understanding of the nonlinear computations in V1. Recent...

Preoperative evaluation of tumour consistency in pituitary macroadenomas: a machine learning-based histogram analysis on conventional T2-weighted MRI.

Neuroradiology
PURPOSE: To evaluate the potential value of machine learning (ML)-based histogram analysis (or first-order texture analysis) on T2-weighted magnetic resonance imaging (MRI) for predicting consistency of pituitary macroadenomas (PMA) and to compare it...

A quantitative SVM approach potentially improves the accuracy of magnetic resonance spectroscopy in the preoperative evaluation of the grades of diffuse gliomas.

NeuroImage. Clinical
OBJECTIVES: To investigate the association between proton magnetic resonance spectroscopy (H-MRS) metabolic features and the grade of gliomas, and to establish a machine-learning model to predict the glioma grade.

Predicting childhood obesity using electronic health records and publicly available data.

PloS one
BACKGROUND: Because of the strong link between childhood obesity and adulthood obesity comorbidities, and the difficulty in decreasing body mass index (BMI) later in life, effective strategies are needed to address this condition in early childhood. ...

Novel pediatric-automated respiratory score using physiologic data and machine learning in asthma.

Pediatric pulmonology
OBJECTIVES: Manual clinical scoring systems are the current standard used for acute asthma clinical care pathways. No automated system exists that assesses disease severity, time course, and treatment impact in pediatric acute severe asthma exacerbat...

Comparison of orthogonal NLP methods for clinical phenotyping and assessment of bone scan utilization among prostate cancer patients.

Journal of biomedical informatics
OBJECTIVE: Clinical care guidelines recommend that newly diagnosed prostate cancer patients at high risk for metastatic spread receive a bone scan prior to treatment and that low risk patients not receive it. The objective was to develop an automated...

Artificial Neural Network Learns Clinical Assessment of Spasticity in Modified Ashworth Scale.

Archives of physical medicine and rehabilitation
OBJECTIVE: To propose an artificial intelligence (AI)-based decision-making rule in modified Ashworth scale (MAS) that draws maximum agreement from multiple human raters and to analyze how various biomechanical parameters affect scores in MAS.