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Evaluation of blood- and urine-derived biomarkers for machine learning prediction models of osteoarthritis in elderly patients: A feasibility study.

Computer methods and programs in biomedicine
BACKGROUND: Osteoarthritis (OA) is a common degenerative joint disease, particularly affecting individuals aged >50 years. It deteriorates quality of life and restricts physical activity in the elderly. Early diagnosis of OA is crucial for effective ...

Deep reinforcement learning for Type 1 Diabetes: Dual PPO controller for personalized insulin management.

Computers in biology and medicine
BACKGROUND: Managing blood glucose levels in Type 1 Diabetes Mellitus (T1DM) is essential to prevent complications. Traditional insulin delivery methods often require significant patient involvement, limiting automation. Reinforcement Learning (RL)-b...

Portable ECG and PCG wireless acquisition system and multiscale CNN feature fusion Bi-LSTM network for coronary artery disease diagnosis.

Computers in biology and medicine
Coronary artery disease (CAD) is a major cause of mortality, especially among aging populations, making timely and accurate diagnosis essential. In this work, a portable wireless device powered by artificial intelligence for CAD detection is proposed...

Automatic cough detection via a multi-sensor smart garment using machine learning.

Computers in biology and medicine
Coughing behavior is associated with conditions such as sleep apnea, asthma, and chronic obstructive pulmonary disorder and can severely affect quality of life in those affected. In this context, coughing quantification is often important, but routin...

Artificial Intelligence-Enabled Prediction of Heart Failure Risk From Single-Lead Electrocardiograms.

JAMA cardiology
IMPORTANCE: Despite the availability of disease-modifying therapies, scalable strategies for heart failure (HF) risk stratification remain elusive. Portable devices capable of recording single-lead electrocardiograms (ECGs) may enable large-scale com...

Whole Brain 3D T1 Mapping in Multiple Sclerosis Using Standard Clinical Images Compared to MP2RAGE and MR Fingerprinting.

NMR in biomedicine
Quantitative T1 and T2 mapping is a useful tool to assess properties of healthy and diseased tissues. However, clinical diagnostic imaging remains dominated by relaxation-weighted imaging without direct collection of relaxation maps. Dedicated resear...

Artificial intelligence-driven microRNA signature for early detection of gastric cancer: discovery and clinical functional exploration.

British journal of cancer
BACKGROUND: Gastric cancer (GC) is a leading cause of cancer-related deaths worldwide, with late-stage diagnoses frequently leading to poor outcomes. This underscores the need for effective early-stage gastric cancer (ESGC) diagnostics.

Radiation oncology patients' perceptions of artificial intelligence and machine learning in cancer care: A multi-centre cross-sectional study.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
AIM: The use of artificial intelligence (AI) and machine learning (ML) is increasingly widespread in radiation oncology. However, patient engagement to date has been poor. Respect for persons in the healthcare setting and the principle of informed co...