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Brain-wide input-output analysis of tuberal nucleus somatostatin neurons reveals hierarchical circuits for orchestrating feeding behavior.

Nature communications
Feeding is an innate behavior critical for survival but is also influenced by many non-nutritional factors such as emotion, social context and environmental conditions. Recently, tuberal nucleus somatostatin (SST) neurons have been identified as a ke...

FPGA implementation of deep learning architecture for ankylosing spondylitis detection from MRI.

Scientific reports
Ankylosing Spondylitis (AS), commonly known as Bechterew's disease, is a complex, potentially disabling disease that develops slowly over time and progresses to radiographic sacroiliitis. The etiology of this disease is poorly understood, making it d...

Automated ejection fraction and risk stratification in cardiomyopathy patients with diverse LV geometry using 2D echocardiography.

Scientific reports
Cardiomyopathy often alters left ventricular geometry (LVG), impairing cardiac function. We developed a deep learning (DL) model to estimate left ventricular ejection fraction (LVEF) from echocardiographic images while accounting for LVG variability ...

Development and validation of an AI-enabled oral score using large-scale dental data.

Scientific reports
This research introduces Oral Score Basic (OS-B), a novel Artificial Intelligence (AI) derived methodology designed to provide a comprehensive, objective assessment of individual teeth and overall oral health, initially focused on dental conditions. ...

Automated sleep staging model for older adults based on CWT and deep learning.

Scientific reports
Sleep staging plays a crucial role in the diagnosis and treatment of sleep disorders. Traditional sleep staging requires manual classification by professional technicians based on the characteristic features of each sleep stage. This process is time-...

Predicting cisplatin response in cholangiocarcinoma patients using chromosome pattern and related gene expression.

Scientific reports
Cholangiocarcinoma (CCA) is a prevalent bile duct cancer with limited treatment options. Cisplatin-based chemotherapy is a common approach, but response rates vary. Recently, chromosome aberrations have emerged as predictors of chemotherapy response ...

Different prefrontal cortex activity patterns in bipolar and unipolar depression during verbal fluency tasks based on functional near infrared spectroscopy study.

Scientific reports
This study aimed to investigate the functionality of the prefrontal cortex in patients with unipolar depression (UD) and bipolar depression (BD) using functional near-infrared spectroscopy (fNIRS) during a verbal fluency task (VFT). Additionally, it ...

Screening biomarkers related to cholesterol metabolism in osteoarthritis based on transcriptomics.

Scientific reports
Cholesterol metabolism-related genes (CMRGs) have been associated with osteoarthritis (OA), but their specific regulatory mechanisms remain unclear. This study aimed to investigate the role of CMRGs in OA and provide new insights into its treatment. ...

Cuff-less blood pressure monitoring via PPG signals using a hybrid CNN-BiLSTM deep learning model with attention mechanism.

Scientific reports
Blood pressure (BP) serves as a fundamental indicator of cardiovascular health, measuring the force exerted by circulating blood against arterial walls during each heartbeat. This paper introduces an advanced deep learning framework for precise, non-...

Development and validation of a modified SOFA score for mortality prediction in candidemia patients.

Scientific reports
Candidemia is a life-threatening bloodstream infection associated with high mortality rates, particularly in critically ill patients. Accurate risk stratification is crucial for timely intervention and could improve patient outcomes. This study aimed...