AIMC Topic: Mice

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Neurotransmitter networks in mouse prefrontal cortex are reconfigured by isoflurane anesthesia.

Journal of neurophysiology Apr 29, 2020
This study quantified eight small-molecule neurotransmitters collected simultaneously from prefrontal cortex of C57BL/6J mice ( = 23) during wakefulness and during isoflurane anesthesia (1.3%). Using isoflurane anesthesia as an independent variable e...
Microdialysis Unconsciousness Isoflurane Wakefulness Anesthesia Anesthetics, Inhalation Adenosine Acetylcholine Nerve Net Mice, Inbred C57BL Norepinephrine Prefrontal Cortex Mice Machine Learning Animals Male
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Efficient Position Decoding Methods Based on Fluorescence Calcium Imaging in the Mouse Hippocampus.

Neural computation Apr 28, 2020
Large-scale fluorescence calcium imaging methods have become widely adopted for studies of long-term hippocampal and cortical neuronal dynamics. Pyramidal neurons of the rodent hippocampus show spatial tuning in freely foraging or head-fixed navigati...
Action Potentials Mice, Inbred C57BL Unsupervised Machine Learning Animals Optical Imaging Male Calcium Signaling Mice Supervised Machine Learning Hippocampus Female
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Robust classification of cell cycle phase and biological feature extraction by image-based deep learning.

Molecular biology of the cell Apr 22, 2020
Across the cell cycle, the subcellular organization undergoes major spatiotemporal changes that could in principle contain biological features that could potentially represent cell cycle phase. We applied convolutional neural network-based classifier...
Image Processing, Computer-Assisted Mice Cell Line Microscopy, Fluorescence Humans Animals Deep Learning NIH 3T3 Cells Cell Cycle Golgi Apparatus HeLa Cells Microtubules Cell Nucleus
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Population coupling predicts the plasticity of stimulus responses in cortical circuits.

eLife Apr 21, 2020
Some neurons have stimulus responses that are stable over days, whereas other neurons have highly plastic stimulus responses. Using a recurrent network model, we explore whether this could be due to an underlying diversity in their synaptic plasticit...
Brain Animals Neuronal Plasticity Mice Humans Models, Neurological Neural Networks, Computer Nerve Net Neurons
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Deep Learning of Spatiotemporal Filtering for Fast Super-Resolution Ultrasound Imaging.

IEEE transactions on ultrasonics, ferroelectrics, and frequency control Apr 15, 2020
Super-resolution ultrasound (SR-US) imaging is a new technique that breaks the diffraction limit and allows visualization of microvascular structures down to tens of micrometers. The image processing methods for the spatiotemporal filtering needed in...
Mammary Neoplasms, Experimental Signal Processing, Computer-Assisted Microbubbles Mice Contrast Media Mice, Nude Neural Networks, Computer Cell Line, Tumor Female Image Processing, Computer-Assisted Deep Learning Animals Ultrasonography
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Towards a fully automated surveillance of well-being status in laboratory mice using deep learning: Starting with facial expression analysis.

PloS one Apr 15, 2020
Assessing the well-being of an animal is hindered by the limitations of efficient communication between humans and animals. Instead of direct communication, a variety of parameters are employed to evaluate the well-being of an animal. Especially in t...
Castration Datasets as Topic Deep Learning Female Behavior, Animal Animal Welfare Animals, Laboratory Animals Mice Anesthetics Facial Expression Laboratory Animal Science Male Pain, Postoperative
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Brain tumor classification of virtual NMR voxels based on realistic blood vessel-induced spin dephasing using support vector machines.

NMR in biomedicine Apr 14, 2020
Remodeling of tissue microvasculature commonly promotes neoplastic growth; however, there is no imaging modality in oncology yet that noninvasively quantifies microvascular changes in clinical routine. Although blood capillaries cannot be resolved in...
Brain Support Vector Machine Brain Neoplasms Magnetic Resonance Imaging Magnetic Resonance Spectroscopy Animals Mice
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Nondestructive Detection of Targeted Microbubbles Using Dual-Mode Data and Deep Learning for Real-Time Ultrasound Molecular Imaging.

IEEE transactions on medical imaging Apr 9, 2020
Ultrasound molecular imaging (UMI) is enabled by targeted microbubbles (MBs), which are highly reflective ultrasound contrast agents that bind to specific biomarkers. Distinguishing between adherent MBs and background signals can be challenging in vi...
Molecular Imaging Microbubbles Ultrasonography Mice Contrast Media Humans Animals Deep Learning
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Biohorology and biomarkers of aging: Current state-of-the-art, challenges and opportunities.

Ageing research reviews Apr 6, 2020
The aging process results in multiple traceable footprints, which can be quantified and used to estimate an organism's age. Examples of such aging biomarkers include epigenetic changes, telomere attrition, and alterations in gene expression and metab...
Humans Biomarkers Animals Aging Mice Neural Networks, Computer Machine Learning Algorithms
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Investigation of Machine Learning Approaches for Traumatic Brain Injury Classification via EEG Assessment in Mice.

Sensors (Basel, Switzerland) Apr 4, 2020
Due to the difficulties and complications in the quantitative assessment of traumatic brain injury (TBI) and its increasing relevance in today's world, robust detection of TBI has become more significant than ever. In this work, we investigate severa...
Animals Male Mice Electroencephalography Technology Assessment, Biomedical Brain Injuries, Traumatic Machine Learning Mice, Inbred C57BL
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