AIMC Topic: Middle Aged

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Increased Global and Regional Connectivity in Propofol-induced Unconsciousness: Human Intracranial Electroencephalography Study.

Anesthesiology
BACKGROUND: The conscious state is maintained through intact communication between brain regions. However, studies on global and regional connectivity changes in unconscious state have been inconsistent. These inconsistencies could arise from unclear...

A Tc1- and Th1-T-lymphocyte-rich tumor microenvironment is a hallmark of MSI colorectal cancer.

The Journal of pathology
Microsatellite instability is a strong predictor of response to immune checkpoint therapy and patient outcome in colorectal cancer. Although enrichment of distinct T-cell subpopulations has been determined to impact the response to immune checkpoint ...

Clinical implementation of AI-based screening for risk for opioid use disorder in hospitalized adults.

Nature medicine
Adults with opioid use disorder (OUD) are at increased risk for opioid-related complications and repeated hospital admissions. Routine screening for patients at risk for an OUD to prevent complications is not standard practice in many hospitals, lead...

Effect of a ChatGPT-based digital counseling intervention on anxiety and depression in patients with cancer: A prospective, randomized trial.

European journal of cancer (Oxford, England : 1990)
BACKGROUND: Psychological distress is prevalent among newly diagnosed cancer patients, often exacerbating treatment-related anxiety and depression. Artificial intelligence (AI)-driven interventions, such as large language models (LLMs), offer scalabl...

A Neural Network Model for Intelligent Classification of Distal Radius Fractures Using Statistical Shape Model Extraction Features.

Orthopaedic surgery
OBJECTIVE: Distal radius fractures account for 12%-17% of all fractures, with accurate classification being crucial for proper treatment planning. Studies have shown that in emergency settings, the misdiagnosis rate of hand/wrist fractures can reach ...

Early prediction of neoadjuvant therapy response in breast cancer using MRI-based neural networks: data from the ACRIN 6698 trial and a prospective Chinese cohort.

Breast cancer research : BCR
BACKGROUND: Early prediction of treatment response to neoadjuvant therapy (NAT) in breast cancer patients can facilitate timely adjustment of treatment regimens. We aimed to develop and validate a MRI-based enhanced self-attention network (MESN) for ...

Deep learning assisted retinal microvasculature assessment and cerebral small vessel disease in Fabry disease.

Orphanet journal of rare diseases
PURPOSE: The aim of this study was to assess retinal microvascular parameters (RMPs) in Fabry disease (FD) using deep learning, and analyze the correlation with brain lesions related to cerebral small vessel disease (CSVD).

Machine learning models to predict osteoporosis in patients with chronic kidney disease stage 3-5 and end-stage kidney disease.

Scientific reports
Chronic kidney disease-mineral bone disorder is a common complication in patients with chronic kidney disease (CKD) and end-stage kidney disease (ESKD), and it increases the risk of osteoporosis and fractures. This study aimed to develop predictive m...

Explainable machine learning model based on EEG, ECG, and clinical features for predicting neurological outcomes in cardiac arrest patient.

Scientific reports
Early and accurate prediction of neurological outcomes in comatose patients following cardiac arrest is critical for informed clinical decision-making. Existing studies have predominantly focused on EEG for assessing brain injury, with some exploring...

Development and validation of a framework for registration of whole-mount radical prostatectomy histopathology with three-dimensional transrectal ultrasound.

BMC urology
PURPOSE: Artificial intelligence (AI) has the potential to improve diagnostic imaging on multiple levels. To develop and validate these AI-assisted modalities a reliable dataset is of utmost importance. The registration of imaging to pathology is an ...