AIMC Topic: Middle Aged

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Machine learning identification of NK cell immune characteristics in hepatocellular carcinoma based on single-cell sequencing and bulk RNA sequencing.

Genes & genomics
BACKGROUND: Hepatocellular carcinoma (HCC) is a highly malignant tumor; however, its immune microenvironment and mechanisms remain elusive. Single-cell sequencing allows for the exploration of immune characteristics within tumor at the cellular level...

Combining metabolomics and machine learning to discover biomarkers for early-stage breast cancer diagnosis.

PloS one
There is an urgent need for better biomarkers for the detection of early-stage breast cancer. Utilizing untargeted metabolomics and lipidomics in conjunction with advanced data mining approaches for metabolism-centric biomarker discovery and validati...

Patient public perspectives on digital colorectal cancer surgery (DALLAS).

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
INTRODUCTION: The importance of patient perspectives is increasingly appreciated in clinical practice and academia with formal engagement processes developing worldwide. Digital surgery encompasses intraoperative patient data (including surgical vide...

Racial and Ethnic Disparities in Predictive Accuracy of Machine Learning Algorithms Developed Using a National Database for 30-Day Complications Following Total Joint Arthroplasty.

The Journal of arthroplasty
BACKGROUND: While predictive capabilities of machine learning (ML) algorithms for hip and knee total joint arthroplasty (TJA) have been demonstrated in previous studies, their performance in racial and ethnic minority patients has not been investigat...

A machine learning tool for identifying newly diagnosed heart failure in individuals with known diabetes in primary care.

ESC heart failure
AIMS: We aimed to create a predictive model utilizing machine learning (ML) to identify new cases of congestive heart failure (CHF) in individuals with diabetes in primary health care (PHC) through the analysis of diagnostic data.

A deep learning-based, real-time image report system for linear EUS.

Gastrointestinal endoscopy
BACKGROUND AND AIMS: The integrity of image acquisition is critical for biliopancreatic EUS reporting, significantly affecting the quality of EUS examinations and disease-related decision-making. However, the quality of EUS reports varies among endos...

Development of machine learning model for predicting prolonged operation time in lumbar stenosis undergoing posterior lumbar interbody fusion: a multicenter study.

The spine journal : official journal of the North American Spine Society
BACKGROUND CONTEXT: Longer posterior lumbar interbody fusion (PLIF) surgeries for individuals with lumbar spinal stenosis are linked to more complications and negatively affect recovery after the operation. Therefore, there is a critical need for a m...

Grading of diabetic retinopathy using a pre-segmenting deep learning classification model: Validation of an automated algorithm.

Acta ophthalmologica
PURPOSE: To validate the performance of autonomous diabetic retinopathy (DR) grading by comparing a human grader and a self-developed deep-learning (DL) algorithm with gold-standard evaluation.

External evaluation of a commercial artificial intelligence-augmented digital auscultation platform in valvular heart disease detection using echocardiography as reference standard.

International journal of cardiology
OBJECTIVE: There are few studies evaluating the accuracy of commercially available AI-powered digital auscultation platforms in detecting valvular heart disease (VHD). Therefore, the utility of these systems for diagnosing clinically significant VHD ...

Development of a machine learning model for precision prognosis of rapid kidney function decline in people with diabetes and chronic kidney disease.

Diabetes research and clinical practice
AIMS: To develop a machine learning model for predicting rapid kidney function decline in people with type 2 diabetes (T2D) and chronic kidney disease (CKD) and to pinpoint key modifiable risk factors for targeted interventions.