AIMC Topic: Motor Neurons

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Memristive Circuit Implementation of Caenorhabditis Elegans Mechanism for Neuromorphic Computing.

IEEE transactions on neural networks and learning systems
To overcome the energy efficiency bottleneck of the von Neumann architecture and scaling limit of silicon transistors, an emerging but promising solution is neuromorphic computing, a new computing paradigm inspired by how biological neural networks h...

Digital Biomarker for Muscle Function Assessment Using Surface Electromyography With Electrical Stimulation and a Non-Invasive Wearable Device.

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
Sarcopenia is a comprehensive degenerative disease with the progressive loss of skeletal muscle mass with age, accompanied by the loss of muscle strength and muscle dysfunction. Individuals with unmanaged sarcopenia may experience adverse outcomes. P...

Classification of Action Potentials With High Variability Using Convolutional Neural Network for Motor Unit Tracking.

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
The reliable classification of motor unit action potentials (MUAPs) provides the possibility of tracking motor unit (MU) activities. However, the variation of MUAP profiles caused by multiple factors in realistic conditions challenges the accurate cl...

A generic neural network model to estimate populational neural activity for robust neural decoding.

Computers in biology and medicine
BACKGROUND: Robust and continuous neural decoding is crucial for reliable and intuitive neural-machine interactions. This study developed a novel generic neural network model that can continuously predict finger forces based on decoded populational m...

Image-based deep learning reveals the responses of human motor neurons to stress and VCP-related ALS.

Neuropathology and applied neurobiology
AIMS: Although morphological attributes of cells and their substructures are recognised readouts of physiological or pathophysiological states, these have been relatively understudied in amyotrophic lateral sclerosis (ALS) research.

Emerging of new bioartificial corticospinal motor synergies using a robotic additional thumb.

Scientific reports
It is likely that when using an artificially augmented hand with six fingers, the natural five plus a robotic one, corticospinal motor synergies controlling grasping actions might be different. However, no direct neurophysiological evidence for this ...

The CPGs for Limbed Locomotion-Facts and Fiction.

International journal of molecular sciences
The neuronal networks that generate locomotion are well understood in swimming animals such as the lamprey, zebrafish and tadpole. The networks controlling locomotion in tetrapods remain, however, still enigmatic with an intricate motor pattern requi...

Prediction Model of Amyotrophic Lateral Sclerosis by Deep Learning with Patient Induced Pluripotent Stem Cells.

Annals of neurology
In amyotrophic lateral sclerosis (ALS), early diagnosis is essential for both current and potential treatments. To find a supportive approach for the diagnosis, we constructed an artificial intelligence-based prediction model of ALS using induced plu...

Neural Interactions in Developing Rhythmogenic Spinal Networks: Insights From Computational Modeling.

Frontiers in neural circuits
The mechanisms involved in generation of rhythmic locomotor activity in the mammalian spinal cord remain poorly understood. These mechanisms supposedly rely on both intrinsic properties of constituting neurons and interactions between them. A subset ...

A Knowledge-Based Machine Learning Approach to Gene Prioritisation in Amyotrophic Lateral Sclerosis.

Genes
Amyotrophic lateral sclerosis is a neurodegenerative disease of the upper and lower motor neurons resulting in death from neuromuscular respiratory failure, typically within two to five years of first symptoms. Several rare disruptive gene variants h...