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Multivariate Analysis

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Quantitative Longitudinal Predictions of Alzheimer's Disease by Multi-Modal Predictive Learning.

Journal of Alzheimer's disease : JAD
BACKGROUND: Quantitatively predicting the progression of Alzheimer's disease (AD) in an individual on a continuous scale, such as the Alzheimer's Disease Assessment Scale-cognitive (ADAS-cog) scores, is informative for a personalized approach as oppo...

A statistically rigorous deep neural network approach to predict mortality in trauma patients admitted to the intensive care unit.

The journal of trauma and acute care surgery
BACKGROUND: Trauma patients admitted to critical care are at high risk of mortality because of their injuries. Our aim was to develop a machine learning-based model to predict mortality using Fahad-Liaqat-Ahmad Intensive Machine (FLAIM) framework. We...

Next-Generation Radiogenomics Sequencing for Prediction of EGFR and KRAS Mutation Status in NSCLC Patients Using Multimodal Imaging and Machine Learning Algorithms.

Molecular imaging and biology
PURPOSE: Considerable progress has been made in the assessment and management of non-small cell lung cancer (NSCLC) patients based on mutation status in the epidermal growth factor receptor (EGFR) and Kirsten rat sarcoma viral oncogene (KRAS). At the...

Modeling and measurement of signaling outcomes affecting decision making in noisy intracellular networks using machine learning methods.

Integrative biology : quantitative biosciences from nano to macro
Characterization of decision-making in cells in response to received signals is of importance for understanding how cell fate is determined. The problem becomes multi-faceted and complex when we consider cellular heterogeneity and dynamics of biochem...

Multivariate Data Analysis and Machine Learning for Prediction of MCI-to-AD Conversion.

Advances in experimental medicine and biology
There has always been a need for discovering efficient and dependable Alzheimer's disease (AD) diagnostic biomarkers. Like the majority of diseases, the earlier the diagnosis, the most effective the treatment. (Semi)-automated structural magnetic res...

Multi-omics integration-a comparison of unsupervised clustering methodologies.

Briefings in bioinformatics
With the recent developments in the field of multi-omics integration, the interest in factors such as data preprocessing, choice of the integration method and the number of different omics considered had increased. In this work, the impact of these f...

Decision tree (DT), generalized regression neural network (GR) and multivariate adaptive regression splines (MARS) models for sediment transport in sewer pipes.

Water science and technology : a journal of the International Association on Water Pollution Research
Sediment deposition in sewers and urban drainage systems has great effect on the hydraulic capacity of the channel. In this respect, the self-cleansing concept has been widely used for sewers and urban drainage systems design. This study investigates...

The Decision Decoding ToolBOX (DDTBOX) - A Multivariate Pattern Analysis Toolbox for Event-Related Potentials.

Neuroinformatics
In recent years, neuroimaging research in cognitive neuroscience has increasingly used multivariate pattern analysis (MVPA) to investigate higher cognitive functions. Here we present DDTBOX, an open-source MVPA toolbox for electroencephalography (EEG...