AIMC Topic: Neoadjuvant Therapy
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Multitask Deep Learning Based on Longitudinal CT Images Facilitates Prediction of Lymph Node Metastasis and Survival in Chemotherapy-Treated Gastric Cancer.
Cancer research
Jul 2, 2025
UNLABELLED: Accurate preoperative assessment of lymph node metastasis (LNM) and overall survival (OS) status is essential for patients with locally advanced gastric cancer receiving neoadjuvant chemotherapy, providing timely guidance for clinical dec...
Machine learning prediction of pathological complete response to neoadjuvant chemotherapy with peritumoral breast tumor ultrasound radiomics: compare with intratumoral radiomics and clinicopathologic predictors.
Breast cancer research and treatment
Jul 1, 2025
PURPOSE: Noninvasive, accurate and novel approaches to predict patients who will achieve pathological complete response (pCR) after neoadjuvant chemotherapy (NAC) could assist treatment strategies. The aim of this study was to explore the application...
Radiomics-based machine learning in prediction of response to neoadjuvant chemotherapy in osteosarcoma: A systematic review and meta-analysis.
Clinical imaging
Jul 1, 2025
BACKGROUND AND AIMS: Osteosarcoma (OS) is the most common primary bone malignancy, and neoadjuvant chemotherapy (NAC) improves survival rates. However, OS heterogeneity results in variable treatment responses, highlighting the need for reliable, non-...
[Progress in neoadjuvant immunotherapy for locally advanced rectal cancer].
Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery
Jun 25, 2025
Neoadjuvant chemoradiotherapy (NACRT) is the standard treatment for locally advanced rectal cancer (LARC), yet the pathological complete response (pCR) rates remain suboptimal. The introduction of immunotherapy has opened new avenues for LARC managem...
Non-Invasive Tumor Budding Evaluation and Correlation with Treatment Response in Bladder Cancer: A Multi-Center Cohort Study.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Jun 1, 2025
The clinical benefits of neoadjuvant chemoimmunotherapy (NACI) are demonstrated in patients with bladder cancer (BCa); however, more than half fail to achieve a pathological complete response (pCR). This study utilizes multi-center cohorts of 2322 pa...
[Current treatment status and future perspectives of advanced gallbladder cancer].
Zhonghua wai ke za zhi [Chinese journal of surgery]
Jun 1, 2025
Gallbladder cancer has an insidious onset,and most of the cases are in advanced stage at the time of diagnosis,with unfavorable prognosis. Radical surgery is the only potential curative method for gallbladder cancer at present,but radical surgery of ...
Clinical prediction of pathological complete response in breast cancer: a machine learning study.
BMC cancer
May 23, 2025
BACKGROUND: This study aimed to develop and validate machine learning models to predict pathological complete response (pCR) after neoadjuvant therapy in patients with breast cancer patients.
Artificial intelligence generated 3D body composition predicts dose modifications in patients undergoing neoadjuvant chemotherapy for rectal cancer.
Journal of cancer research and clinical oncology
May 16, 2025
PURPOSE: Chemotherapy administration is a balancing act between giving enough to achieve the desired tumour response while limiting adverse effects. Chemotherapy dosing is based on body surface area (BSA). Emerging evidence suggests body composition ...
Deep learning MRI-based radiomic models for predicting recurrence in locally advanced nasopharyngeal carcinoma after neoadjuvant chemoradiotherapy: a multi-center study.
Clinical & experimental metastasis
May 15, 2025
Local recurrence and distant metastasis were a common manifestation of locoregionally advanced nasopharyngeal carcinoma (LA-NPC) after neoadjuvant chemoradiotherapy (NACT). To validate the clinical value of MRI radiomic models based on deep learning ...
Machine learning algorithms integrating positron emission tomography/computed tomography features to predict pathological complete response after neoadjuvant chemoimmunotherapy in lung cancer.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
May 6, 2025
OBJECTIVES: Reliable methods for predicting pathological complete response (pCR) in non-small cell lung cancer (NSCLC) patients undergoing neoadjuvant chemoimmunotherapy are still under exploration. Although Fluorine-18 fluorodeoxyglucose-positron em...
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