AIMC Topic: Neoplasm Grading

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Clinical use of machine learning-based pathomics signature for diagnosis and survival prediction of bladder cancer.

Cancer science
Traditional histopathology performed by pathologists by the naked eye is insufficient for accurate and efficient diagnosis of bladder cancer (BCa). We collected 643 H&E-stained BCa images from Shanghai General Hospital and The Cancer Genome Atlas (TC...

Current Status and Quality of Machine Learning-Based Radiomics Studies for Glioma Grading: A Systematic Review.

Oncology
INTRODUCTION: Radiomics now has significant momentum in the era of precision medicine. Glioma is one of the pathologies that has been extensively evaluated by radiomics. However, this technique has not been incorporated into clinical practice. In thi...

Using deep learning to predict microvascular invasion in hepatocellular carcinoma based on dynamic contrast-enhanced MRI combined with clinical parameters.

Journal of cancer research and clinical oncology
PURPOSE: Microvascular invasion (MVI) is a critical determinant of the early recurrence and poor prognosis of patients with hepatocellular carcinoma (HCC). Prediction of MVI status is clinically significant for the decision of treatment strategies an...

Can artificial intelligence overtake human intelligence on the bumpy road towards glioma therapy?

Medical oncology (Northwood, London, England)
Gliomas are one of the most devastating primary brain tumors which impose significant management challenges to the clinicians. The aggressive behaviour of gliomas is mainly attributed to their rapid proliferation, unravelled genomics and the blood-br...

A multi-phase deep CNN based mitosis detection framework for breast cancer histopathological images.

Scientific reports
The mitotic activity index is a key prognostic measure in tumour grading. Microscopy based detection of mitotic nuclei is a significant overhead and necessitates automation. This work proposes deep CNN based multi-phase mitosis detection framework "M...

MRI-based clinical-radiomics model predicts tumor response before treatment in locally advanced rectal cancer.

Scientific reports
Neoadjuvant chemo-radiotherapy (CRT) followed by total mesorectal excision (TME) represents the standard treatment for patients with locally advanced (≥ T3 or N+) rectal cancer (LARC). Approximately 15% of patients with LARC shows a complete response...

Diffusion histology imaging differentiates distinct pediatric brain tumor histology.

Scientific reports
High-grade pediatric brain tumors exhibit the highest cancer mortality rates in children. While conventional MRI has been widely adopted for examining pediatric high-grade brain tumors clinically, accurate neuroimaging detection and differentiation o...

Deep learning-based grading of ductal carcinoma in situ in breast histopathology images.

Laboratory investigation; a journal of technical methods and pathology
Ductal carcinoma in situ (DCIS) is a non-invasive breast cancer that can progress into invasive ductal carcinoma (IDC). Studies suggest DCIS is often overtreated since a considerable part of DCIS lesions may never progress into IDC. Lower grade lesio...

Quantitative analysis of abnormalities in gynecologic cytopathology with deep learning.

Laboratory investigation; a journal of technical methods and pathology
Cervical cancer is one of the most frequent cancers in women worldwide, yet the early detection and treatment of lesions via regular cervical screening have led to a drastic reduction in the mortality rate. However, the routine examination of screeni...

Deep Learning Regression for Prostate Cancer Detection and Grading in Bi-Parametric MRI.

IEEE transactions on bio-medical engineering
One of the most common types of cancer in men is prostate cancer (PCa). Biopsies guided by bi-parametric magnetic resonance imaging (MRI) can aid PCa diagnosis. Previous works have mostly focused on either detection or classification of PCa from MRI....