AIMC Topic: Neoplasm Grading

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Combined molecular subtyping, grading, and segmentation of glioma using multi-task deep learning.

Neuro-oncology
BACKGROUND: Accurate characterization of glioma is crucial for clinical decision making. A delineation of the tumor is also desirable in the initial decision stages but is time-consuming. Previously, deep learning methods have been developed that can...

Comparison of Supervised and Self-Supervised Deep Representations Trained on Histological Images.

Studies in health technology and informatics
Self-supervised methods gain more and more attention, especially in the medical domain, where the number of labeled data is limited. They provide results on par or superior to their fully supervised competitors, yet the difference between information...

Noninvasive Glioma Grading with Deep Learning: A Pilot Study.

Studies in health technology and informatics
Gliomas are the most common neuroepithelial brain tumors, different by various biological tissue types and prognosis. They could be graded with four levels according to the 2007 WHO classification. The emergence of non-invasive histological and molec...

An artificial neural network model based on DNA damage response genes to predict outcomes of lower-grade glioma patients.

Briefings in bioinformatics
Although the prognosis of lower-grade glioma (LGG) patients is better than others, outcomes are highly heterogeneous. Isocitrate dehydrogenase (IDH) mutation and 1p/19q codeletion status can identify patient subsets with different prognosis. However,...

Learning a Triplet Embedding Distance to Represent Gleason Patterns.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Gleason grade stratification is the main histological standard to determine the severity and progression of prostate cancer. Nonetheless, there is a high variability on disease diagnosis among expert pathologists (kappa lower than 0.44). End-to-end d...

Artificial Intelligence-assisted Prostate Cancer Diagnosis: Radiologic-Pathologic Correlation.

Radiographics : a review publication of the Radiological Society of North America, Inc
The classic prostate cancer (PCa) diagnostic pathway that is based on prostate-specific antigen (PSA) levels and the findings of digital rectal examination followed by systematic biopsy has shown multiple limitations. The use of multiparametric MRI (...

Artificial intelligence in prostate histopathology: where are we in 2021?

Current opinion in urology
PURPOSE OF REVIEW: Artificial intelligence has made an entrance into mainstream applications of daily life but the clinical deployment of artificial intelligence-supported histological analysis is still at infancy. Recent years have seen a surge in t...

Cone Beam CT (CBCT) Based Synthetic CT Generation Using Deep Learning Methods for Dose Calculation of Nasopharyngeal Carcinoma Radiotherapy.

Technology in cancer research & treatment
To generate synthetic CT (sCT) images with high quality from CBCT and planning CT (pCT) for dose calculation by using deep learning methods. 169 NPC patients with a total of 20926 slices of CBCT and pCT images were included. In this study the Cycle...

Differentiation of Intrahepatic Cholangiocarcinoma and Hepatic Lymphoma Based on Radiomics and Machine Learning in Contrast-Enhanced Computer Tomography.

Technology in cancer research & treatment
This study aimed to explore the ability of texture parameters combining with machine learning methods in distinguishing intrahepatic cholangiocarcinoma (ICCA) and hepatic lymphoma (HL). A total of 28 patients with HL and 101 patients with ICCA were...

Reimagining T Staging Through Artificial Intelligence and Machine Learning Image Processing Approaches in Digital Pathology.

JCO clinical cancer informatics
Tumor stage and grade, visually assessed by pathologists from evaluation of pathology images in conjunction with radiographic imaging techniques, have been linked to outcome, progression, and survival for a number of cancers. The gold standard of sta...