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Neoplasm Invasiveness

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Artificial intelligence-enhanced magnetic resonance imaging-based pre-operative staging in patients with endometrial cancer.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
OBJECTIVE: Evaluation of prognostic factors is crucial in patients with endometrial cancer for optimal treatment planning and prognosis assessment. This study proposes a deep learning pipeline for tumor and uterus segmentation from magnetic resonance...

Computed tomography-based fully automated artificial intelligence model to predict extrapancreatic perineural invasion in pancreatic ductal adenocarcinoma.

International journal of surgery (London, England)
BACKGROUND: Extrapancreatic perineural invasion (EPNI) increases the risk of postoperative recurrence in pancreatic ductal adenocarcinoma (PDAC). This study aimed to develop and validate a computed tomography (CT)-based, fully automated preoperative ...

Deep learning-based lymph node metastasis status predicts prognosis from muscle-invasive bladder cancer histopathology.

World journal of urology
PURPOSE: To develop a deep learning (DL) model based on primary tumor tissue to predict the lymph node metastasis (LNM) status of muscle invasive bladder cancer (MIBC), while validating the prognostic value of the predicted aiN score in MIBC patients...

Machine learning model based on preoperative contrast-enhanced CT and clinical features to predict perineural invasion in gallbladder carcinoma patients.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
BACKGROUND: Perineural invasion (PNI) is an independent prognostic risk factor for gallbladder carcinoma (GBC). However, there is currently no reliable method for the preoperative noninvasive prediction of PNI.

Radiomics integration based on intratumoral and peritumoral computed tomography improves the diagnostic efficiency of invasiveness in patients with pure ground-glass nodules: a machine learning, cross-sectional, bicentric study.

Journal of cardiothoracic surgery
BACKGROUND: Radiomics has shown promise in the diagnosis and prognosis of lung cancer. Here, we investigated the performance of computed tomography-based radiomic features, extracted from gross tumor volume (GTV), peritumoral volume (PTV), and GTV + ...

Identifying invasiveness to aid lung adenocarcinoma diagnosis using deep learning and pathomics.

Scientific reports
Most classification efforts for primary subtypes of lung adenocarcinoma (LUAD) have not yet been integrated into clinical practice. This study explores the feasibility of combining deep learning and pathomics to identify tumor invasiveness in LUAD pa...

Machine Learning Accurately Predicts Muscle Invasion of Bladder Cancer Based on Three miRNAs.

Journal of cellular and molecular medicine
The aim of this study was to validate the diagnostic potential of four previously identified miRNAs in two independent cohorts and to develop accurate classification models to predict invasiveness of bladder cancer. Furthermore, molecular subtypes we...

Deep learning and radiomics for gastric cancer serosal invasion: automated segmentation and multi-machine learning from two centers.

Journal of cancer research and clinical oncology
OBJECTIVE: The objective of this study is to develop an automated method for segmenting spleen computed tomography (CT) images using a deep learning model. This approach is intended to address the limitations of manual segmentation, which is known to...

MRI-Based Topology Deep Learning Model for Noninvasive Prediction of Microvascular Invasion and Assisting Prognostic Stratification in HCC.

Liver international : official journal of the International Association for the Study of the Liver
BACKGROUND & AIMS: Microvascular invasion (MVI) is associated with poor prognosis in hepatocellular carcinoma (HCC). Topology may improve the predictive performance and interpretability of deep learning (DL). We aimed to develop and externally valida...