AIMC Topic: Neoplasms

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Graphene quantum dots as singlet oxygen producer or radical quencher - The matter of functionalization with urea/thiourea.

Materials science & engineering. C, Materials for biological applications
Due to their low cost and possible green synthesis, high stability and resistance to photobleaching, graphene quantum dots (GQDs) can be considered as one of the class of carbon nanomaterials which may have great potential as an agent for photosensit...

Artificial intelligence in cancer diagnosis and prognosis: Opportunities and challenges.

Cancer letters
Cancer is an aggressive disease with a low median survival rate. Ironically, the treatment process is long and very costly due to its high recurrence and mortality rates. Accurate early diagnosis and prognosis prediction of cancer are essential to en...

Synthesis and biological characterization of MnZnEuDyFeO nanoparticles by sonochemical approach.

Materials science & engineering. C, Materials for biological applications
Metallic nanoparticles (NPs) possess unique properties which makes them attractive candidates for various applications especially in field of experimental medicine and drug delivery. Many approaches were developed to synthesize divers and customized ...

Analysis of Decision Tree and K-Nearest Neighbor Algorithm in the Classification of Breast Cancer.

Asian Pacific journal of cancer prevention : APJCP
OBJECTIVE: The death rate of breast tumour is falling as there is progress in its research area. However, it is the most common disease among women. It is a great challenge in designing a machine learning model to evaluate the performance of the clas...

DeepMiR2GO: Inferring Functions of Human MicroRNAs Using a Deep Multi-Label Classification Model.

International journal of molecular sciences
MicroRNAs (miRNAs) are a highly abundant collection of functional non-coding RNAs involved in cellular regulation and various complex human diseases. Although a large number of miRNAs have been identified, most of their physiological functions remain...

Standard operating procedure for curation and clinical interpretation of variants in cancer.

Genome medicine
Manually curated variant knowledgebases and their associated knowledge models are serving an increasingly important role in distributing and interpreting variants in cancer. These knowledgebases vary in their level of public accessibility, and the co...

SGL-SVM: A novel method for tumor classification via support vector machine with sparse group Lasso.

Journal of theoretical biology
At present, with the in-depth study of gene expression data, the significant role of tumor classification in clinical medicine has become more apparent. In particular, the sparse characteristics of gene expression data within and between groups. Ther...

Prediction of the Health Effects of Food Peptides and Elucidation of the Mode-of-action Using Multi-task Graph Convolutional Neural Network.

Molecular informatics
Food proteins work not only as nutrients but also modulators for the physiological functions of the human body. The physiological functions of food proteins are basically regulated by peptides encrypted in food protein sequences (food peptides). In t...

Analyzing gene expression data for pediatric and adult cancer diagnosis using logic learning machine and standard supervised methods.

BMC bioinformatics
BACKGROUND: Logic Learning Machine (LLM) is an innovative method of supervised analysis capable of constructing models based on simple and intelligible rules. In this investigation the performance of LLM in classifying patients with cancer was evalua...

Unsupervised feature selection algorithm for multiclass cancer classification of gene expression RNA-Seq data.

Genomics
This paper presents a Grouping Genetic Algorithm (GGA) to solve a maximally diverse grouping problem. It has been applied for the classification of an unbalanced database of 801 samples of gene expression RNA-Seq data in 5 types of cancer. The sample...