IEEE journal of biomedical and health informatics
Jul 31, 2019
Neuroimaging and genetic biomarkers have been widely studied from discriminative perspectives towards Alzheimer's disease (AD) classification, since neuroanatomical patterns and genetic variants are jointly critical indicators for AD diagnosis. Gener...
White matter hyperintensities (WMH) or white matter lesions exhibit high variability in their characteristics both at population- and subject-level, making their detection a challenging task. Population-level factors such as age, vascular risk factor...
Machine learning approaches may provide ways to link brain activation patterns to behavior at an individual-subject level. Using a comparative performance analysis, Jollans and colleagues (Neuroimage, 2019) highlight in a recent paper key considerati...
AJNR. American journal of neuroradiology
Jul 25, 2019
BACKGROUND AND PURPOSE: Most brain lesions are characterized by hyperintense signal on FLAIR. We sought to develop an automated deep learning-based method for segmentation of abnormalities on FLAIR and volumetric quantification on clinical brain MRIs...
Neuroscience and biobehavioral reviews
Jul 19, 2019
Pattern classification and stratification approaches have increasingly been used in research on Autism Spectrum Disorder (ASD) over the last ten years with the goal of translation towards clinical applicability. Here, we present an extensive scoping ...
Combining machine learning with neuroimaging data has a great potential for early diagnosis of mild cognitive impairment (MCI) and Alzheimer's disease (AD). However, it remains unclear how well the classifiers built on one population can predict MCI/...
The differential diagnosis of primary central nervous system lymphoma from glioblastoma multiforme (GBM) is essential due to the difference in treatment strategies. This study retrospectively reviewed 77 patients (24 with lymphoma and 53 with GBM) to...
Biological psychiatry. Cognitive neuroscience and neuroimaging
Jun 21, 2019
BACKGROUND: The field of psychiatry has long sought biomarkers that can objectively diagnose patients, predict treatment response, or identify individuals at risk of illness onset. However, reliable psychiatric biomarkers have yet to emerge. The rece...
Carotid-artery atherosclerosis (CA) contributes significantly to overall morbidity and mortality in ischemic stroke. We propose a machine learning technique to automatically identify subjects with CA from a heterogeneous cohort of magnetic resonance ...
BACKGROUND: Human cortical primary sulci are relatively stable landmarks and commonly observed across the population. Despite their stability, the primary sulci exhibit phenotypic variability.