AIMC Topic: Nitric Oxide

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Anticancer and anti-inflammatory activities of girinimbine isolated from .

Drug design, development and therapy
Therapy that directly targets apoptosis and/or inflammation could be highly effective for the treatment of cancer. is an edible herb that has been traditionally used for cancer treatment as well as inflammation. Here, we describe that girinimbine, a...

Icariin improves eNOS/NO pathway to prohibit the atherogenesis of apolipoprotein E-null mice.

Canadian journal of physiology and pharmacology
Impaired endothelial nitric oxide synthase (eNOS)/nitric oxide (NO) pathway induces atherogenesis. The present study examined whether icariin improves the eNOS/NO pathway to prohibit the atherogenesis of apolipoprotein E-null (ApoE) mice. In vitro, p...

NITRIC OXIDE INHIBITORY ACTIVITY OF (LOGANIACEAE) LEAF EXTRACTS AND FRACTIONS.

African journal of traditional, complementary, and alternative medicines : AJTCAM
BACKGROUND: The study was aimed at determining the anti-inflammatory activity of fractions and extracts obtained from leaves on a mediator of inflammation nitric oxide (NO).

Exposure to fipronil elevates systolic blood pressure and disturbs related biomarkers in plasma of rats.

Environmental toxicology and pharmacology
Recent reports show that fipronil affects non-target organisms, including environmental species populations and potentially humans. We aimed to examine if fipronil exposure affects the systolic blood pressure and related biomarkers. Thus, fipronil wa...

Amelioration of Chronic Ethanol Administration-Induced Learning and Memory Impairments by High-Intensity Interval Training (HIIT) and Ritalin.

Brain and behavior
OBJECTIVES: The current study aimed to investigate the impacts of 8-week high-intensity interval training (HIIT) and Ritalin (RIT), alone and in combination, on cognitive functions and hippocampal oxidative parameters following chronic ethanol consum...

Polysaccharides extracted from the roots of Bupleurum chinense DC modulates macrophage functions.

Chinese journal of natural medicines
The present study aimed to investigate the effects of polysaccharides extracted from Bupleurum chinense DC (BCPs) on macrophage functions. In the in vivo experiment, 1 mL of 5% sodium thioglycollate was injected into the abdomen of the mice on Day 0 ...

THE ESTROGENS / CHROMIUM INTERACTION IN THE NITRIC OXIDE GENERATION.

Acta poloniae pharmaceutica
The interaction of estrogens with environmental toxins in free radicals generation: reactive oxygen species (ROS) or reactive nitrogen species (RNS) which participates in cancerogenesis is not yet recognized. Chromium(VI) is widely present in environ...

The Effect of Artemisia fragrans Willd: Essential Oil on Inducible Nitric Oxide Synthase Gene Expression and Nitric Oxide Production in Lipopolysaccharide-stimulated Murine Macrophage Cell Line.

Iranian journal of allergy, asthma, and immunology
The genus Artemisia is estimated to comprise over 800 species with anti-cancer, anti-fungal, anti-oxidant and anti-inflammatory properties. Artemisia fragrans (A. fragrans), a species that belongs to genus Artemisia, is rich in monoterpenes and sesqu...

[The Protective Effect of Inhibition of PARP-1 on Inflammation Induced by PM2.5 in Human Bronchial Epithelial Cell Line.].

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition
OBJECTIVES: To explore whether the inhibition of poly ADP-ribose polymerase-1(PARP-1) could attenuated inflammation induced by fine particulate matter (PM2.5) in human bronchial epithelial cell line.