AIMC Topic: Optic Disk
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Analysis of 2-dimensional regional differences in the peripapillary scleral fibroblast cytoskeleton of normotensive and hypertensive mouse eyes.
Scientific reports
Jul 1, 2025
These studies aimed to study the mechanisms of glaucomatous peripapillary scleral (PPS) remodeling by investigating IOP-induced changes in fibroblast actin-collagen alignment and nuclear morphology in mouse PPS. Cryosections from the optic nerve head...
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International ophthalmology
Jun 27, 2025
UNLABELLED: Early detection of glaucoma represents a vital factor in securing vision while the disease retains its position as one of the central causes of blindness worldwide. The current glaucoma screening strategies with expert interpretation depe...
Enhanced glaucoma classification through advanced segmentation by integrating cup-to-disc ratio and neuro-retinal rim features.
Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Apr 28, 2025
Glaucoma is a progressive eye condition caused by high intraocular fluid pressure, damaging the optic nerve, leading to gradual, irreversible vision loss, often without noticeable symptoms. Subtle signs like mild eye redness, slightly blurred vision,...
Optimized glaucoma detection using HCCNN with PSO-driven hyperparameter tuning.
Biomedical physics & engineering express
Apr 22, 2025
. This study is focused on creating an effective glaucoma detection system employing a Hybrid Centric Convolutional Neural Network (HCCNN) model. By using Particle Swarm Optimization (PSO), classification accuracy is increased and computing complexit...
Sharper insights: Adaptive ellipse-template for robust fovea localization in challenging retinal landscapes.
Computers in biology and medicine
Apr 20, 2025
Automated identification of retinal landmarks, particularly the fovea is crucial for diagnosing diabetic retinopathy and other ocular diseases. But accurate identification is challenging due to varying contrast, color irregularities, anatomical struc...
Robust semi-automatic vessel tracing in the human retinal image by an instance segmentation neural network.
Science advances
Apr 4, 2025
Vasculature morphology and hierarchy are essential for blood perfusion. Human retinal circulation is an intricate vascular system emerging and remerging at the optic nerve head (ONH). Tracing retinal vascular branching from ONH can allow detailed mor...
Capsule network-based deep learning for early and accurate diabetic retinopathy detection.
International ophthalmology
Feb 18, 2025
Glaucoma, an optic nerve disease resulting in blindness if left untreated, is a difficult condition in healthcare in view of its diagnostic difficulties. Past approaches are based on assessment of the fundus images and the size of the cup and the dis...
Rim learning framework based on TS-GAN: A new paradigm of automated glaucoma screening from fundus images.
Computers in biology and medicine
Feb 3, 2025
Glaucoma detection from fundus images often relies on biomarkers such as the Cup-to-Disc Ratio (CDR) and Rim-to-Disc Ratio (RDR). However, precise segmentation of the optic cup and disc is challenging due to low-contrast boundaries and the interferen...
Systematic application of saliency maps to explain the decisions of convolutional neural networks for glaucoma diagnosis based on disc and cup geometry.
Biomedical physics & engineering express
Jan 21, 2025
This paper systematically evaluates saliency methods as explainability tools for convolutional neural networks trained to diagnose glaucoma using simplified eye fundus images that contain only disc and cup outlines. These simplified images, a methodo...
CC-TransXNet: a hybrid CNN-transformer network for automatic segmentation of optic cup and optic disk from fundus images.
Medical & biological engineering & computing
Nov 27, 2024
Accurate segmentation of the optic disk (OD) and optic cup (OC) regions of the optic nerve head is a critical step in glaucoma diagnosis. Existing architectures based on convolutional neural networks (CNNs) still suffer from insufficient global infor...
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