AIMC Topic: Papillomaviridae
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Challenges and Opportunities for Global Cervical Cancer Elimination: How Can We Build a Model for Other Cancers?
American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting
Jun 11, 2025
Cervical cancer remains a leading cause of cancer-related death among women globally, despite the availability of effective prevention through human papillomavirus (HPV) vaccination and HPV-based screening. This review explores the state-of-the-art t...
Molecular detection of hrHPV-induced high-grade squamous intraepithelial lesions of the cervix through a targeted RNA next generation sequencing assay.
Molecular medicine (Cambridge, Mass.)
May 30, 2025
BACKGROUND: Cervical cancer screening programs are increasingly relying on sensitive molecular approaches as primary tests to detect high-risk human papillomaviruses (hrHPV), the causative agents of cervix cancer. Although hrHPV infection is a pre-re...
Advancements in fluorescent nanobiosensors for HPV detection: from integrating nanomaterials to DNA nanotechnology.
International journal of biological macromolecules
Apr 28, 2025
Human papillomavirus (HPV) is a leading cause of cervical cancer and other malignancies, necessitating the development of highly sensitive and specific detection tools. This review explores recent advancements in fluorescent nanobiosensors (FNBS) for...
Deep learning informed multimodal fusion of radiology and pathology to predict outcomes in HPV-associated oropharyngeal squamous cell carcinoma.
EBioMedicine
Mar 22, 2025
BACKGROUND: We aim to predict outcomes of human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (OPSCC), a subtype of head and neck cancer characterized with improved clinical outcome and better response to therapy. Pathology an...
Analysis of AI foundation model features decodes the histopathologic landscape of HPV-positive head and neck squamous cell carcinomas.
Oral oncology
Mar 4, 2025
OBJECTIVES: Human papillomavirus (HPV) influences the pathobiology of Head and Neck Squamous Cell Carcinomas (HSNCCs). While deep learning shows promise in detecting HPV from hematoxylin and eosin (H&E) stained slides, the histologic features utilize...
Human papillomavirus (HPV) prediction for oropharyngeal cancer based on CT by using off-the-shelf features: A dual-dataset study.
Journal of applied clinical medical physics
Mar 2, 2025
BACKGROUND: This study aims to develop a novel predictive model for determining human papillomavirus (HPV) presence in oropharyngeal cancer using computed tomography (CT). Current image-based HPV prediction methods are hindered by high computational ...
Prognosis of p16 and Human Papillomavirus Discordant Oropharyngeal Cancers and the Exploration of Using Natural Language Processing to Analyze Free-Text Pathology Reports.
JCO clinical cancer informatics
Feb 18, 2025
PURPOSE: Treatment deintensification for human papillomavirus-positive (HPV+)-associated oropharyngeal cancer (OPC) has been the catalyst of experts worldwide. In situ hybridization is optimal to identify HPV+ OPC, but immunohistochemistry for its su...
Application of Machine Learning Algorithms for Risk Stratification and Efficacy Evaluation in Cervical Cancer Screening among the ASCUS/LSIL Population: Evidence from the Korean HPV Cohort Study.
Cancer research and treatment
Sep 6, 2024
PURPOSE: We assessed human papillomavirus (HPV) genotype-based risk stratification and the efficacy of cytology testing for cervical cancer screening in patients with atypical squamous cells of undetermined significance (ASCUS)/low-grade squamous int...
Genome composition-based deep learning predicts oncogenic potential of HPVs.
Frontiers in cellular and infection microbiology
Jul 22, 2024
Human papillomaviruses (HPVs) account for more than 30% of cancer cases, with definite identification of the oncogenic role of viral and genes. However, the identification of high-risk HPV genotypes has largely relied on lagged biological explorati...
Development, Validation, and Implementation of an Augmented Multiwell, Multitarget Quantitative PCR for the Analysis of Human Papillomavirus Genotyping through Software Automation, Data Science, and Artificial Intelligence.
The Journal of molecular diagnostics : JMD
Jul 5, 2024
The value of human papillomavirus (HPV) testing for cervical cancer screening is well established; however, its use as a primary screening option or as a reflex test after atypical cytology results is now gaining wider acceptance. The importance of f...
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