Parkinson's disease (PD) remains a condition without a cure, though its early manifestations can be managed effectively by medical professionals. This underscores the significance of early detection of PD. It has been widely demonstrated that handwri...
This study investigates the classification of individuals as healthy or at risk of Parkinson's disease using machine learning (ML) models, focusing on the impact of dataset size and preprocessing techniques on model performance. Four datasets are cre...
IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
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Dynamic brain networks are more effective than static networks in characterizing the evolving patterns of brain functional connectivity, making them a more promising tool for diagnosing neurodegenerative diseases. However, existing classification met...
Parkinson's disease ranks as the second most prevalent neurological disorder after Alzheimer's disease. Convolutional neural networks (CNNs) have been extensively employed in Parkinson's disease (PD) detection using MR images. However, CNN models gen...
Freezing of gait (FoG) is a debilitating symptom of Parkinson's disease that severely impacts patients' mobility and quality of life. To minimize the risk of falls and injuries associated with FoG, it is crucial to develop highly accurate FoG detecti...
BACKGROUND: Parkinson's disease (PD), a prevalent neurodegenerative disorder in the aging population, poses significant challenges in unraveling its pathogenesis and progression. A key area of investigation is the disruption of oncological metabolic ...
There is strong interest in using the gut microbiome for Parkinson's disease (PD) diagnosis and treatment. However, a consensus on PD-associated microbiome features and a multi-study assessment of their diagnostic value is lacking. Here, we present a...
BACKGROUND: Postural instability and gait difficulties are key symptoms of Parkinson's disease (PD), elevating the risk of falls substantially. Falls afflict 35% to 90% of PD patients, representing a major challenge in managing the condition. Accurat...
INTRODUCTION: Deep brain stimulation (DBS) is a proven effective treatment for Parkinson's disease (PD). However, titrating DBS stimulation parameters is a labourious process and requires frequent hospital visits. Additionally, its current applicatio...