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Patient-Specific Modeling

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Natural Language Understanding Performance & Use Considerations in Virtual Medical Encounters.

Studies in health technology and informatics
A virtual standardized patient (VSP) prototype was tested for natural language understanding (NLU) performance. The conversational VSP was evaluated in a controlled 61 subject study over four repetitions of a patient case. The prototype achieved more...

Dynamic Parameter Identification of Subject-Specific Body Segment Parameters Using Robotics Formalism: Case Study Head Complex.

Journal of biomechanical engineering
Accurate knowledge of body segment inertia parameters (BSIP) improves the assessment of dynamic analysis based on biomechanical models, which is of paramount importance in fields such as sport activities or impact crash test. Early approaches for BSI...

Neural Network Optimization of Ligament Stiffnesses for the Enhanced Predictive Ability of a Patient-Specific, Computational Foot/Ankle Model.

Journal of biomechanical engineering
Computational models of diarthrodial joints serve to inform the biomechanical function of these structures, and as such, must be supplied appropriate inputs for performance that is representative of actual joint function. Inputs for these models are ...

Machine Learning and Primary Total Knee Arthroplasty: Patient Forecasting for a Patient-Specific Payment Model.

The Journal of arthroplasty
BACKGROUND: Value-based and patient-specific care represent 2 critical areas of focus that have yet to be fully reconciled by today's bundled care model. Using a predictive naïve Bayesian model, the objectives of this study were (1) to develop a mach...

PLATYPUS: A Multiple-View Learning Predictive Framework for Cancer Drug Sensitivity Prediction.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
Cancer is a complex collection of diseases that are to some degree unique to each patient. Precision oncology aims to identify the best drug treatment regime using molecular data on tumor samples. While omics-level data is becoming more widely availa...

Predicting VMAT patient-specific QA results using a support vector classifier trained on treatment plan characteristics and linac QC metrics.

Physics in medicine and biology
The use of treatment plan characteristics to predict patient-specific quality assurance (QA) measurement results has recently been reported as a strategy to help facilitate automated pre-treatment verification workflows or to provide a virtual assess...

Data-driven modeling and prediction of blood glucose dynamics: Machine learning applications in type 1 diabetes.

Artificial intelligence in medicine
BACKGROUND: Diabetes mellitus (DM) is a metabolic disorder that causes abnormal blood glucose (BG) regulation that might result in short and long-term health complications and even death if not properly managed. Currently, there is no cure for diabet...

Automated Muscle Segmentation from Clinical CT Using Bayesian U-Net for Personalized Musculoskeletal Modeling.

IEEE transactions on medical imaging
We propose a method for automatic segmentation of individual muscles from a clinical CT. The method uses Bayesian convolutional neural networks with the U-Net architecture, using Monte Carlo dropout that infers an uncertainty metric in addition to th...

End-to-end semantic segmentation of personalized deep brain structures for non-invasive brain stimulation.

Neural networks : the official journal of the International Neural Network Society
Electro-stimulation or modulation of deep brain regions is commonly used in clinical procedures for the treatment of several nervous system disorders. In particular, transcranial direct current stimulation (tDCS) is widely used as an affordable clini...