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Positron Emission Tomography Computed Tomography

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PSMA PET/CT for prostate cancer diagnosis: current applications and future directions.

Journal of cancer research and clinical oncology
Prostate cancer (PCa) requires improved diagnostic strategies beyond conventional imaging. This review aimed to evaluate the role of prostate-specific membrane antigen positron emission tomography/computed tomography (PSMA PET/CT) in diagnosing advan...

Evaluating Automated Tools for Lesion Detection on F Fluoroestradiol PET/CT Images and Assessment of Concordance with Standard-of-Care Imaging in Metastatic Breast Cancer.

Radiology. Imaging cancer
Purpose To evaluate two automated tools for detecting lesions on fluorine 18 (F) fluoroestradiol (FES) PET/CT images and assess concordance of F-FES PET/CT with standard diagnostic CT and/or F fluorodeoxyglucose (FDG) PET/CT in patients with breast c...

Enhancing F-FDG PET image quality and lesion diagnostic performance across different body mass index using the deep progressive learning reconstruction algorithm.

Cancer imaging : the official publication of the International Cancer Imaging Society
BACKGROUND: As body mass index (BMI) increases, the quality of 2-deoxy-2-[fluorine-18]fluoro-D-glucose (F-FDG) positron emission tomography (PET) images reconstructed with ordered subset expectation maximization (OSEM) declines, negatively impacting ...

Identification of HER2-over-expression, HER2-low-expression, and HER2-zero-expression statuses in breast cancer based on F-FDG PET/CT radiomics.

Cancer imaging : the official publication of the International Cancer Imaging Society
PURPOSE: According to the updated classification system, human epidermal growth factor receptor 2 (HER2) expression statuses are divided into the following three groups: HER2-over-expression, HER2-low-expression, and HER2-zero-expression. HER2-negati...

Machine learning models for enhanced diagnosis and risk assessment of prostate cancer with Ga-PSMA-617 PET/CT.

European journal of radiology
OBJECTIVE: Prostate cancer (PCa) is highly heterogeneous, making early detection of adverse pathological features crucial for improving patient outcomes. This study aims to predict PCa aggressiveness and identify radiomic and protein biomarkers assoc...

Development and validation of pan-cancer lesion segmentation AI-model for whole-body 18F-FDG PET/CT in diverse clinical cohorts.

Computers in biology and medicine
BACKGROUND: This study develops a deep learning-based automated lesion segmentation model for whole-body 3DF-fluorodeoxyglucose (FDG)-Position emission tomography (PET) with computed tomography (CT) images agnostic to disease location and site.

F-FDG PET/CT-based deep learning models and a clinical-metabolic nomogram for predicting high-grade patterns in lung adenocarcinoma.

BMC medical imaging
BACKGROUND: To develop and validate deep learning (DL) and traditional clinical-metabolic (CM) models based on 18 F-FDG PET/CT images for noninvasively predicting high-grade patterns (HGPs) of invasive lung adenocarcinoma (LUAD).

Expanding interpretability through complexity reduction in machine learning-based modelling of cardiovascular disease: A myocardial perfusion imaging PET/CT prognostic study.

European journal of clinical investigation
BACKGROUND: Machine learning-based analysis can be used in myocardial perfusion imaging data to improve risk stratification and the prediction of major adverse cardiovascular events for patients with suspected or established coronary artery disease. ...

Large Language Models in Summarizing Radiology Report Impressions for Lung Cancer in Chinese: Evaluation Study.

Journal of medical Internet research
BACKGROUND: Large language models (LLMs), such as ChatGPT, have demonstrated impressive capabilities in various natural language processing tasks, particularly in text generation. However, their effectiveness in summarizing radiology report impressio...

Machine learning algorithms integrating positron emission tomography/computed tomography features to predict pathological complete response after neoadjuvant chemoimmunotherapy in lung cancer.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
OBJECTIVES: Reliable methods for predicting pathological complete response (pCR) in non-small cell lung cancer (NSCLC) patients undergoing neoadjuvant chemoimmunotherapy are still under exploration. Although Fluorine-18 fluorodeoxyglucose-positron em...