AIMC Topic: Positron-Emission Tomography

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Development and validation of a machine learning model to predict myocardial blood flow and clinical outcomes from patients' electrocardiograms.

Cell reports. Medicine
We develop a machine learning (ML) model using electrocardiography (ECG) to predict myocardial blood flow reserve (MFR) and assess its prognostic value for major adverse cardiovascular events (MACEs). Using 3,639 ECG-positron emission tomography (PET...

Artificial intelligence-based analysis of behavior and brain images in cocaine-self-administered marmosets.

Journal of neuroscience methods
BACKGROUND: The sophisticated behavioral and cognitive repertoires of non-human primates (NHPs) make them suitable subjects for studies involving cocaine self-administration (SA) schedules. However, ethical considerations, adherence to the 3Rs princi...

Deep learning-based techniques for estimating high-quality full-dose positron emission tomography images from low-dose scans: a systematic review.

BMC medical imaging
This systematic review aimed to evaluate the potential of deep learning algorithms for converting low-dose Positron Emission Tomography (PET) images to full-dose PET images in different body regions. A total of 55 articles published between 2017 and ...

PET radiomics-based lymphovascular invasion prediction in lung cancer using multiple segmentation and multi-machine learning algorithms.

Physical and engineering sciences in medicine
The current study aimed to predict lymphovascular invasion (LVI) using multiple machine learning algorithms and multi-segmentation positron emission tomography (PET) radiomics in non-small cell lung cancer (NSCLC) patients, offering new avenues for p...

A Scoping Review of Machine-Learning Derived Radiomic Analysis of CT and PET Imaging to Investigate Atherosclerotic Cardiovascular Disease.

Tomography (Ann Arbor, Mich.)
BACKGROUND: Cardiovascular disease affects the carotid arteries, coronary arteries, aorta and the peripheral arteries. Radiomics involves the extraction of quantitative data from imaging features that are imperceptible to the eye. Radiomics analysis ...

Advancing Tau PET Quantification in Alzheimer Disease with Machine Learning: Introducing THETA, a Novel Tau Summary Measure.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Alzheimer disease (AD) exhibits spatially heterogeneous 3- or 4-repeat tau deposition across participants. Our overall goal was to develop an automated method to quantify the heterogeneous burden of tau deposition into a single number that would be c...

Deep learning applications for quantitative and qualitative PET in PET/MR: technical and clinical unmet needs.

Magma (New York, N.Y.)
We aim to provide an overview of technical and clinical unmet needs in deep learning (DL) applications for quantitative and qualitative PET in PET/MR, with a focus on attenuation correction, image enhancement, motion correction, kinetic modeling, and...

Physically informed deep neural networks for metabolite-corrected plasma input function estimation in dynamic PET imaging.

Computer methods and programs in biomedicine
INTRODUCTION: We propose a novel approach for the non-invasive quantification of dynamic PET imaging data, focusing on the arterial input function (AIF) without the need for invasive arterial cannulation.

An end-to-end deep learning pipeline to derive blood input with partial volume corrections for automated parametric brain PET mapping.

Biomedical physics & engineering express
Dynamic 2-[18F] fluoro-2-deoxy-D-glucose positron emission tomography (dFDG-PET) for human brain imaging has considerable clinical potential, yet its utilization remains limited. A key challenge in the quantitative analysis of dFDG-PET is characteriz...