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Positron-Emission Tomography

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Higher SNR PET image prediction using a deep learning model and MRI image.

Physics in medicine and biology
PET images often suffer poor signal-to-noise ratio (SNR). Our objective is to improve the SNR of PET images using a deep neural network (DNN) model and MRI images without requiring any higher SNR PET images in training. Our proposed DNN model consist...

Deep Learning Predicts Lung Cancer Treatment Response from Serial Medical Imaging.

Clinical cancer research : an official journal of the American Association for Cancer Research
PURPOSE: Tumors are continuously evolving biological systems, and medical imaging is uniquely positioned to monitor changes throughout treatment. Although qualitatively tracking lesions over space and time may be trivial, the development of clinicall...

Deep learning only by normal brain PET identify unheralded brain anomalies.

EBioMedicine
BACKGROUND: Recent deep learning models have shown remarkable accuracy for the diagnostic classification. However, they have limitations in clinical application due to the gap between the training cohorts and real-world data. We aimed to develop a mo...

Joint correction of attenuation and scatter in image space using deep convolutional neural networks for dedicated brain F-FDG PET.

Physics in medicine and biology
Dedicated brain positron emission tomography (PET) devices can provide higher-resolution images with much lower doses compared to conventional whole-body PET systems, which is important to support PET neuroimaging and particularly useful for the diag...

Machine learning based hierarchical classification of frontotemporal dementia and Alzheimer's disease.

NeuroImage. Clinical
BACKGROUND: In a clinical setting, an individual subject classification model rather than a group analysis would be more informative. Specifically, the subtlety of cortical atrophy in some frontotemporal dementia (FTD) patients and overlapping patter...

DeepPET: A deep encoder-decoder network for directly solving the PET image reconstruction inverse problem.

Medical image analysis
The purpose of this research was to implement a deep learning network to overcome two of the major bottlenecks in improved image reconstruction for clinical positron emission tomography (PET). These are the lack of an automated means for the optimiza...

Exploit fully automatic low-level segmented PET data for training high-level deep learning algorithms for the corresponding CT data.

PloS one
We present an approach for fully automatic urinary bladder segmentation in CT images with artificial neural networks in this study. Automatic medical image analysis has become an invaluable tool in the different treatment stages of diseases. Especial...

Scaled Subprofile Modeling and Convolutional Neural Networks for the Identification of Parkinson's Disease in 3D Nuclear Imaging Data.

International journal of neural systems
Over the last years convolutional neural networks (CNNs) have shown remarkable results in different image classification tasks, including medical imaging. One area that has been less explored with CNNs is Positron Emission Tomography (PET). Fluorodeo...

MRI-based attenuation correction for brain PET/MRI based on anatomic signature and machine learning.

Physics in medicine and biology
Deriving accurate attenuation maps for PET/MRI remains a challenging problem because MRI voxel intensities are not related to properties of photon attenuation and bone/air interfaces have similarly low signal. This work presents a learning-based meth...

PET Image Reconstruction Using Deep Image Prior.

IEEE transactions on medical imaging
Recently, deep neural networks have been widely and successfully applied in computer vision tasks and have attracted growing interest in medical imaging. One barrier for the application of deep neural networks to medical imaging is the need for large...