International journal of surgery (London, England)
Apr 1, 2025
Detection of biomarkers of breast cancer incurs additional costs and tissue burden. We propose a deep learning-based algorithm (BBMIL) to predict classical biomarkers, immunotherapy-associated gene signatures, and prognosis-associated subtypes direct...
BACKGROUND: While the Cardiometabolic Index (CMI) serves as a novel marker for assessing adipose tissue distribution and metabolic function, its prognostic utility for cardiovascular disease (CVD) events remains incompletely understood. This investig...
BACKGROUND: High-grade gliomas are among the most aggressive and deadly brain tumors, highlighting the critical need for improved prognostic markers and predictive models. Recent studies have identified the expression of IL7R as a significant risk fa...
BMC medical informatics and decision making
Mar 31, 2025
BACKGROUND: Sepsis, a severe systemic response to infection, frequently results in adverse outcomes, underscoring the urgency for prompt and accurate prognostic tools. Machine learning methods such as logistic regression, random forests, and CatBoost...
Prostate cancer (PCa) diagnosis faces significant challenges due to its complex pathological characteristics and insufficient pathologist resources. While deep learning-based image analysis (DLIA) shows promise in enhancing diagnostic accuracy, its a...
PURPOSE: This study aims to investigate the impact of tumor quadrant location on the 5-year early-stage breast cancer survivability prediction using explainable machine learning (ML) models. By integrating these predictive models with Shapley Additiv...
BACKGROUND: Ovarian cancer (OC), owing to its substantial heterogeneity and high invasiveness, has historically been devoid of precise, individualized treatment options. This study aimed to establish integrated consensus subtypes of OC using differen...
The most prevalent malignancy among women is breast cancer; hence, treatment approaches are needed in consideration of tumor characteristics and disease stage but also patient preference. Two surgical options, Mastectomy and Breast Conserving Surgery...
This study aimed to develop a machine learning (ML) model for predicting the risk of acute kidney injury (AKI) in diabetic patients with heart failure (HF) during hospitalization. Using data from 1,457 patients in the MIMIC-IV database, the study ide...
Intratumor heterogeneity (ITH) is involved in tumor evolution and drug resistance. Drug sensitivity shows discrepancy in different breast cancer (BRCA) patients due to ITH. The genes mediating ITH in BRCA and their role in predicting prognosis and dr...