AIMC Topic: Propofol
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Letter to the Editor: A randomised trial to compare the increase in intracranial pressure as correlated with the optic nerve sheath diameter during propofol versus sevoflurane-maintained anesthesia in robot-assisted laparoscopic pelvic surgery.
Journal of robotic surgery
Feb 28, 2022
Propofol Anesthesia Depth Monitoring Based on Self-Attention and Residual Structure Convolutional Neural Network.
Computational and mathematical methods in medicine
Jan 29, 2022
METHODS: We compare nine index values, select CNN+EEG, which has good correlation with BIS index, as an anesthesia state observation index to identify the parameters of the model, and establish a model based on self-attention and dual resistructure c...
Ketofol as an Anesthetic Agent in Patients With Isolated Moderate to Severe Traumatic Brain Injury: A Prospective, Randomized Double-blind Controlled Trial.
Journal of neurosurgical anesthesiology
May 13, 2021
BACKGROUND: The effects of ketofol (propofol and ketamine admixture) on systemic hemodynamics and outcomes in patients undergoing emergency decompressive craniectomy for traumatic brain injury (TBI) are unknown and explored in this study.
Machine learning of EEG spectra classifies unconsciousness during GABAergic anesthesia.
PloS one
May 6, 2021
In current anesthesiology practice, anesthesiologists infer the state of unconsciousness without directly monitoring the brain. Drug- and patient-specific electroencephalographic (EEG) signatures of anesthesia-induced unconsciousness have been identi...
How hot is the hot zone? Computational modelling clarifies the role of parietal and frontoparietal connectivity during anaesthetic-induced loss of consciousness.
NeuroImage
Feb 9, 2021
In recent years, specific cortical networks have been proposed to be crucial for sustaining consciousness, including the posterior hot zone and frontoparietal resting state networks (RSN). Here, we computationally evaluate the relative contributions ...
Effect of different general anaesthetics on ventricular repolarisation in robot-assisted laparoscopic prostatectomy.
Acta anaesthesiologica Scandinavica
Jul 3, 2020
BACKGROUND: Ventricular repolarisation is affected differently by the types of anaesthetics used. This study aimed to compare the effect of different types of anaesthetics on ventricular repolarisation during robot-assisted laparoscopic radical prost...
Propofol affects the growth and metastasis of pancreatic cancer via ADAM8.
Pharmacological reports : PR
Dec 20, 2019
BACKGROUND: Anesthesia is a major component of surgery and recently considered an important regulator of cell phenotypes. Here we aimed to investigate propofol, an anesthesia drug, in suppressing pancreatic cancer (PDAC), focusing on A disintegrin an...
Matrix Metalloproteinase 2
Xenograft Model Antitumor Assays
Neoplasm Metastasis
Humans
MAP Kinase Signaling System
Apoptosis
Animals
Neoplasm Invasiveness
ADAM Proteins
Antineoplastic Agents
Pancreatic Neoplasms
Membrane Proteins
Mice, SCID
Cell Line, Tumor
Matrix Metalloproteinase 9
Cell Proliferation
Propofol
Cell Movement
Use of Multiple EEG Features and Artificial Neural Network to Monitor the Depth of Anesthesia.
Sensors (Basel, Switzerland)
May 31, 2019
The electroencephalogram (EEG) can reflect brain activity and contains abundant information of different anesthetic states of the brain. It has been widely used for monitoring depth of anesthesia (DoA). In this study, we propose a method that combine...
Optimal adaptive control of drug dosing using integral reinforcement learning.
Mathematical biosciences
Feb 5, 2019
In this paper, a reinforcement learning (RL)-based optimal adaptive control approach is proposed for the continuous infusion of a sedative drug to maintain a required level of sedation. To illustrate the proposed method, we use the common anesthetic ...
Potential EEG biomarkers of sedation doses in intensive care patients unveiled by using a machine learning approach.
Journal of neural engineering
Jan 31, 2019
OBJECTIVE: Sedation of neurocritically ill patients is one of the most challenging situation in ICUs. Quantitative knowledge on the sedation effect on brain activity in that complex scenario could help to uncover new markers for sedation assessment. ...
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