Computational and mathematical methods in medicine
Sep 30, 2022
Survival analysis deals with the expected duration of time until one or more events of interest occur. Time to the event of interest may be unobserved, a phenomenon commonly known as right censoring, which renders the analysis of these data challengi...
Analysis of data with a censored survival response and high-dimensional omics measurements is now common. Most of the existing analyses are based on specific (semi)parametric models, in particular the Cox model. Such analyses may be limited by not ha...
BACKGROUND: Prediction models for time-to-event outcomes are commonly used in biomedical research to obtain subject-specific probabilities that aid in making important clinical care decisions. There are several regression and machine learning methods...
PURPOSE: The current study aimed to construct a novel cancer artificial intelligence survival analysis system for predicting the individual mortality risk curves for cervical carcinoma patients receiving different treatments.
BACKGROUND: We collected information on patients with rectal adenocarcinoma in the United States from the Surveillance, Epidemiology, and EndResults (SEER) database. We used this information to establish a model that combined deep learning with a mul...
Multi-state models can capture the different patterns of disease evolution. In particular, the illness-death model is used to follow disease progression from a healthy state to an intermediate state of the disease and to a death-related final state. ...
Neural networks : the official journal of the International Neural Network Society
Dec 29, 2021
An extension of the Neural Additive Model (NAM) called SurvNAM and its modifications are proposed to explain predictions of a black-box machine learning survival model. The method is based on applying the original NAM to solving the explanation probl...
Computational and mathematical methods in medicine
Dec 24, 2021
BACKGROUND: A survival prediction model based on deep learning has higher accuracy than the CPH model in predicting the survival of CCU patients, and it also has a better discrimination ability. We collected information on patients with various disea...
Whole-Slide Histopathology Image (WSI) is generally considered the gold standard for cancer diagnosis and prognosis. Given the large inter-operator variation among pathologists, there is an imperative need to develop machine learning models based on ...
Computational and mathematical methods in medicine
Nov 28, 2021
BACKGROUND: Studies focusing on prediction models are widespread in medicine. There is a trend in applying machine learning (ML) by medical researchers and clinicians. Over the years, multiple ML algorithms have been adapted to censored data. However...