AIMC Topic: Prostatic Neoplasms

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Computerized Classification of Prostate Cancer Gleason Scores from Whole Slide Images.

IEEE/ACM transactions on computational biology and bioinformatics
Histological Gleason grading of tumor patterns is one of the most powerful prognostic predictors in prostate cancer. However, manual analysis and grading performed by pathologists are typically subjective and time-consuming. In this paper, we present...

Robotic radical prostatectomy: analysis of midterm pathologic and oncologic outcomes: A historical series from a high-volume center.

Surgical endoscopy
BACKGROUND: Identifying predictors of positive surgical margins (PSM) and biochemical recurrence (BCR) after radical prostatectomy (RP) may assist clinicians in formulating prognosis. Aim of the study was to report the midterm oncologic outcomes, to ...

The surgical learning curve for salvage robot-assisted radical prostatectomy: a prospective single-surgeon study.

Minerva urology and nephrology
BACKGROUND: The aim of this study was to report the overall results and the learning curve (LC) in salvage robot-assisted radical prostatectomy (sRARP) patients, in terms of morbidity, oncological and functional outcomes in a single surgeon tertiary-...

Deformable MR-CBCT prostate registration using biomechanically constrained deep learning networks.

Medical physics
BACKGROUND AND PURPOSE: Radiotherapeutic dose escalation to dominant intraprostatic lesions (DIL) in prostate cancer could potentially improve tumor control. The purpose of this study was to develop a method to accurately register multiparametric mag...

Development and evaluation of a deep learning based artificial intelligence for automatic identification of gold fiducial markers in an MRI-only prostate radiotherapy workflow.

Physics in medicine and biology
Identification of prostate gold fiducial markers in magnetic resonance imaging (MRI) images is challenging when CT images are not available, due to misclassifications from intra-prostatic calcifications. It is also a time consuming task and automated...

A 3D-2D Hybrid U-Net Convolutional Neural Network Approach to Prostate Organ Segmentation of Multiparametric MRI.

AJR. American journal of roentgenology
OBJECTIVE: Prostate cancer is the most commonly diagnosed cancer in men in the United States with more than 200,000 new cases in 2018. Multiparametric MRI (mpMRI) is increasingly used for prostate cancer evaluation. Prostate organ segmentation is an ...

Metabolomics of Prostate Cancer Gleason Score in Tumor Tissue and Serum.

Molecular cancer research : MCR
Gleason score, a measure of prostate tumor differentiation, is the strongest predictor of lethal prostate cancer at the time of diagnosis. Metabolomic profiling of tumor and of patient serum could identify biomarkers of aggressive disease and lead to...

PCLiON: An Ontology for Data Standardization and Sharing of Prostate Cancer Associated Lifestyles.

International journal of medical informatics
BACKGROUND: Researches on Lifestyle medicine (LM) have emerged in recent years to garner wide attention. Prostate cancer (PCa) could be prevented and treated by positive lifestyles, but the association between lifestyles and PCa is always personalize...