AIMC Topic: Radiotherapy, Intensity-Modulated

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Can knowledge-based planning models validated on ethnically diverse patients lead to global standardisation of external beam radiation therapy for locally advanced cervix cancer?

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
BACKGROUND AND PURPOSE: Knowledge-based planning (KBP) can consistently and efficiently create high-quality Volumetric Arc Therapy (VMAT) plans for cervix cancer. This study describes the cross-validation of two KBP models on geographically distinct ...

Validating knowledge-based volumetric modulated arc therapy plans with a multi-institution model (broad model) using a complete open-loop dataset for prostate cancer.

Physical and engineering sciences in medicine
This study examined the characteristics of the broad model (KBP) through a complete open-loop evaluation of volumetric modulated arc therapy (VMAT) plans for prostate cancer in 30 patients at two institutions. KBP, trained using 561 prostate cancer V...

Deep learning dose prediction to approach Erasmus-iCycle dosimetric plan quality within seconds for instantaneous treatment planning.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
BACKGROUND AND PURPOSE: Fast, high-quality deep learning (DL) prediction of patient-specific 3D dose distributions can enable instantaneous treatment planning (IP), in which the treating physician can evaluate the dose and approve the plan immediatel...

Estimation of heart dose in left breast cancer radiotherapy: Assessment of vDIBH feasibility using the supervised machine learning algorithm.

Journal of applied clinical medical physics
BACKGROUND AND OBJECTIVE: The volunteer deep inspiration breath hold (vDIBH) technique is used to reduce the heart dose in left breast cancer radiotherapy. Many times, it is faced that despite rigorous exercise and training, not all patients get bene...

A prognostic and predictive model based on deep learning to identify optimal candidates for intensity-modulated radiotherapy alone in patients with stage II nasopharyngeal carcinoma: A retrospective multicenter study.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
PURPOSE: To develop and validate a prognostic and predictive model integrating deep learning MRI features and clinical information in patients with stage II nasopharyngeal carcinoma (NPC) to identify patients with a low risk of progression for whom i...

Assessing population-based to personalized planning strategies for head and neck adaptive radiotherapy.

Journal of applied clinical medical physics
PURPOSE: Optimal head-and-neck cancer (HNC) treatment planning requires accurate and feasible planning goals to meet dosimetric constraints and generate robust online adaptive treatment plans. A new x-ray-based adaptive radiotherapy (ART) treatment p...

Breast radiotherapy planning: A decision-making framework using deep learning.

Medical physics
BACKGROUND: Effective breast cancer treatment planning requires balancing tumor control while minimizing radiation exposure to healthy tissues. Choosing between intensity-modulated radiation therapy (IMRT) and three-dimensional conformal radiation th...

Quality and mechanical efficiency of automated knowledge-based planning for volumetric-modulated arc therapy in head and neck cancer.

Journal of applied clinical medical physics
OBJECTIVES: This study aimed to examine the effectiveness of the automated RapidPlan in assessing plan quality and to explore how beam complexity affects the mechanical performance of volumetric modulated arc therapy for head and neck cancers.

Evaluation and comparison of synthetic computed tomography algorithms with 3T MRI for prostate radiotherapy: AI-based versus bulk density method.

Journal of applied clinical medical physics
PURPOSE: Synthetic computed tomography (sCT)-algorithms, which generate computed tomography images from magnetic resonance imaging data, are becoming part of the clinical radiotherapy workflow. The aim of this retrospective study was to evaluate and ...