AIMC Topic: Radiotherapy Planning, Computer-Assisted

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Stochastic frontier analysis as knowledge-based model to improve sparing of organs-at-risk for VMAT-treated prostate cancer.

Physics in medicine and biology
Stochastic frontier analysis (SFA) is used as a novel knowledge-based technique in order to develop a predictive model of dosimetric features from significant geometric parameters describing a patient morphology. 406 patients treated with VMAT for pr...

Dosimetric study on learning-based cone-beam CT correction in adaptive radiation therapy.

Medical dosimetry : official journal of the American Association of Medical Dosimetrists
INTRODUCTION: Cone-beam CT (CBCT) image quality is important for its quantitative analysis in adaptive radiation therapy. However, due to severe artifacts, the CBCTs are primarily used for verifying patient setup only so far. We have developed a lear...

A deep learning- and partial least square regression-based model observer for a low-contrast lesion detection task in CT.

Medical physics
PURPOSE: This work aims to develop a new framework of image quality assessment using deep learning-based model observer (DL-MO) and to validate it in a low-contrast lesion detection task that involves CT images with patient anatomical background.

A modality-adaptive method for segmenting brain tumors and organs-at-risk in radiation therapy planning.

Medical image analysis
In this paper we present a method for simultaneously segmenting brain tumors and an extensive set of organs-at-risk for radiation therapy planning of glioblastomas. The method combines a contrast-adaptive generative model for whole-brain segmentation...

3D radiotherapy dose prediction on head and neck cancer patients with a hierarchically densely connected U-net deep learning architecture.

Physics in medicine and biology
The treatment planning process for patients with head and neck (H&N) cancer is regarded as one of the most complicated due to large target volume, multiple prescription dose levels, and many radiation-sensitive critical structures near the target. Tr...

Automatic Segmentation of the Prostate on CT Images Using Deep Neural Networks (DNN).

International journal of radiation oncology, biology, physics
PURPOSE: Recent advances in deep neural networks (DNNs) have unlocked opportunities for their application for automatic image segmentation. We have evaluated a DNN-based algorithm for automatic segmentation of the prostate gland on a large cohort of ...

Generation of virtual lung single-photon emission computed tomography/CT fusion images for functional avoidance radiotherapy planning using machine learning algorithms.

Journal of medical imaging and radiation oncology
INTRODUCTION: Functional image-guided radiotherapy (RT) planning for normal lung avoidance has recently been introduced. Single-photon emission computed tomography (SPECT)/CT can help identify the functional areas of lungs, but it is associated with ...

Neural Networks for Deep Radiotherapy Dose Analysis and Prediction of Liver SBRT Outcomes.

IEEE journal of biomedical and health informatics
Stereotactic body radiation therapy (SBRT) is a relatively novel treatment modality, with little post-treatment prognostic information reported. This study proposes a novel neural network based paradigm for accurate prediction of liver SBRT outcomes....

Dual-energy CT for automatic organs-at-risk segmentation in brain-tumor patients using a multi-atlas and deep-learning approach.

Scientific reports
In radiotherapy, computed tomography (CT) datasets are mostly used for radiation treatment planning to achieve a high-conformal tumor coverage while optimally sparing healthy tissue surrounding the tumor, referred to as organs-at-risk (OARs). Based o...