AIMC Topic: Reproducibility of Results

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MVP predicts the pathogenicity of missense variants by deep learning.

Nature communications
Accurate pathogenicity prediction of missense variants is critically important in genetic studies and clinical diagnosis. Previously published prediction methods have facilitated the interpretation of missense variants but have limited performance. H...

Sarcoma classification by DNA methylation profiling.

Nature communications
Sarcomas are malignant soft tissue and bone tumours affecting adults, adolescents and children. They represent a morphologically heterogeneous class of tumours and some entities lack defining histopathological features. Therefore, the diagnosis of sa...

Investigating the use of a two-stage attention-aware convolutional neural network for the automated diagnosis of otitis media from tympanic membrane images: a prediction model development and validation study.

BMJ open
OBJECTIVES: This study investigated the usefulness and performance of a two-stage attention-aware convolutional neural network (CNN) for the automated diagnosis of otitis media from tympanic membrane (TM) images.

Kinematics and workspace analysis of 4SPRR-SPR parallel robots.

PloS one
The 4SPRR-SPR parallel robot, which has considerable potential for application in the field of machining, is a novel closed-loop mechanism with a high rigid-weight ratio. Kinematics and workspace analyses of the 4SPRR-SPR parallel robot are key requi...

Evaluation of transfer learning in deep convolutional neural network models for cardiac short axis slice classification.

Scientific reports
In computer-aided analysis of cardiac MRI data, segmentations of the left ventricle (LV) and myocardium are performed to quantify LV ejection fraction and LV mass, and they are performed after the identification of a short axis slice coverage, where ...

Dynamics of Systemic Inflammation as a Function of Developmental Stage in Pediatric Acute Liver Failure.

Frontiers in immunology
The Pediatric Acute Liver Failure (PALF) study is a multicenter, observational cohort study of infants and children diagnosed with this complex clinical syndrome. Outcomes in PALF reflect interactions among the child's clinical condition, response to...

Validity and precision of the International Physical Activity Questionnaire for climacteric women using computational intelligence techniques.

PloS one
This study aimed to evaluate the validity and precision of the International Physical Activity Questionnaire (IPAQ) for climacteric women using computational intelligence techniques. The instrument was applied to 873 women aged between 40 and 65 year...

ELASPIC2 (EL2): Combining Contextualized Language Models and Graph Neural Networks to Predict Effects of Mutations.

Journal of molecular biology
The ELASPIC web server allows users to evaluate the effect of mutations on protein folding and protein-protein interaction on a proteome-wide scale. It uses homology models of proteins and protein-protein interactions, which have been precalculated f...

Age-group determination of living individuals using first molar images based on artificial intelligence.

Scientific reports
Dental age estimation of living individuals is difficult and challenging, and there is no consensus method in adults with permanent dentition. Thus, we aimed to provide an accurate and robust artificial intelligence (AI)-based diagnostic system for a...