AIMC Topic: Reproducibility of Results

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A study of generalizability of recurrent neural network-based predictive models for heart failure onset risk using a large and heterogeneous EHR data set.

Journal of biomedical informatics
Recently, recurrent neural networks (RNNs) have been applied in predicting disease onset risks with Electronic Health Record (EHR) data. While these models demonstrated promising results on relatively small data sets, the generalizability and transfe...

Fetal health status prediction based on maternal clinical history using machine learning techniques.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: Congenital anomalies are seen at 1-3% of the population, probabilities of which are tried to be found out primarily through double, triple and quad tests during pregnancy. Also, ultrasonographical evaluations of fetuses enha...

From lexical regularities to axiomatic patterns for the quality assurance of biomedical terminologies and ontologies.

Journal of biomedical informatics
Ontologies and terminologies have been identified as key resources for the achievement of semantic interoperability in biomedical domains. The development of ontologies is performed as a joint work by domain experts and knowledge engineers. The maint...

PrESOgenesis: A two-layer multi-label predictor for identifying fertility-related proteins using support vector machine and pseudo amino acid composition approach.

Scientific reports
Successful spermatogenesis and oogenesis are the two genetically independent processes preceding embryo development. To date, several fertility-related proteins have been described in mammalian species. Nevertheless, further studies are required to d...

Protein-Protein Interactions Prediction via Multimodal Deep Polynomial Network and Regularized Extreme Learning Machine.

IEEE journal of biomedical and health informatics
Predicting the protein-protein interactions (PPIs) has played an important role in many applications. Hence, a novel computational method for PPIs prediction is highly desirable. PPIs endow with protein amino acid mutation rate and two physicochemica...

Reliability, validity, and clinical feasibility of a rapid and objective assessment of post-stroke deficits in hand proprioception.

Journal of neuroengineering and rehabilitation
BACKGROUND: Proprioceptive function can be affected after neurological injuries such as stroke. Severe and persistent proprioceptive impairments may be associated with a poor functional recovery after stroke. To better understand their role in the re...

Fuzzy decision support systems to diagnose musculoskeletal disorders: A systematic literature review.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: Musculoskeletal disorders (MSDs) are one of the most important causes of disability with a high prevalence. The accurate and timely diagnosis of these disorders is often difficult. Clinical decision support systems (CDSSs) c...

Machine-learning-derived classifier predicts absence of persistent pain after breast cancer surgery with high accuracy.

Breast cancer research and treatment
BACKGROUND: Prevention of persistent pain following breast cancer surgery, via early identification of patients at high risk, is a clinical need. Supervised machine-learning was used to identify parameters that predict persistence of significant pain...

Assessment of the Diagnostic Accuracy of Biparametric Magnetic Resonance Imaging for Prostate Cancer in Biopsy-Naive Men: The Biparametric MRI for Detection of Prostate Cancer (BIDOC) Study.

JAMA network open
IMPORTANCE: Multiparametric magnetic resonance imaging (MRI) enhances detection and risk stratification for significant prostate cancer but is time-consuming (approximately 40 minutes) and expensive. Rapid and simpler (approximately 15-minute) bipara...