AIMC Topic: Reproducibility of Results

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A systematic comparison of feature space effects on disease classifier performance for phenotype identification of five diseases.

Journal of biomedical informatics
Automated phenotype identification plays a critical role in cohort selection and bioinformatics data mining. Natural Language Processing (NLP)-informed classification techniques can robustly identify phenotypes in unstructured medical notes. In this ...

Design, testing and modelling of a novel robotic system for trans-oesophageal ultrasound.

The international journal of medical robotics + computer assisted surgery : MRCAS
BACKGROUND: Trans-oesophageal echocardiography (TOE) has been widely utilized for cardiac disease diagnosis and interventional procedure guidance. However, the TOE operator is required to manually manipulate the probe, often for long periods of time ...

MATEPRED-A-SVM-Based Prediction Method for Multidrug And Toxin Extrusion (MATE) Proteins.

Computational biology and chemistry
The growth and spread of drug resistance in bacteria have been well established in both mankind and beasts and thus is a serious public health concern. Due to the increasing problem of drug resistance, control of infectious diseases like diarrhea, pn...

Multi-scale deep networks and regression forests for direct bi-ventricular volume estimation.

Medical image analysis
Direct estimation of cardiac ventricular volumes has become increasingly popular and important in cardiac function analysis due to its effectiveness and efficiency by avoiding an intermediate segmentation step. However, existing methods rely on eithe...

Objective assessment of robotic surgical skill using instrument contact vibrations.

Surgical endoscopy
BACKGROUND: Surgical skill evaluation ordinarily requires tedious video review and survey completion, while new automatic approaches focus on evaluating the quality of the surgeon's movements in free space. Robotic surgical instrument vibrations are ...

A mutation profile for top-k patient search exploiting Gene-Ontology and orthogonal non-negative matrix factorization.

Bioinformatics (Oxford, England)
MOTIVATION: As the quantity of genomic mutation data increases, the likelihood of finding patients with similar genomic profiles, for various disease inferences, increases. However, so does the difficulty in identifying them. Similarity search based ...

Identification of Heat Shock Protein families and J-protein types by incorporating Dipeptide Composition into Chou's general PseAAC.

Computer methods and programs in biomedicine
Heat Shock Proteins (HSPs) are the substantial ingredients for cell growth and viability, which are found in all living organisms. HSPs manage the process of folding and unfolding of proteins, the quality of newly synthesized proteins and protecting ...

Retinal vessel segmentation using multi-scale textons derived from keypoints.

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
This paper presents a retinal vessel segmentation algorithm which uses a texton dictionary to classify vessel/non-vessel pixels. However, in contrast to previous work where filter parameters are learnt from manually labelled image pixels our filter p...