AIMC Topic: Retrospective Studies

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Artificial intelligence-enabled safety monitoring in Alzheimer's disease clinical trials.

The journal of prevention of Alzheimer's disease
BACKGROUND: Investigators conducting clinical trials have an ethical, scientific, and regulatory obligation to protect the safety of trial participants. Traditionally, safety monitoring includes manual review and coding of adverse event data by exper...

Development of Time-Aggregated Machine Learning Model for Relapse Prediction in Pediatric Crohn's Disease.

Clinical and translational gastroenterology
INTRODUCTION: Pediatric Crohn's disease (CD) easily progresses to an active disease compared with adult CD, making it important to predict and minimize CD relapses. However, prediction of relapse at various time points (TPs) during pediatric CD remai...

Identification of genomic alteration and prognosis using pathomics-based artificial intelligence in oral leukoplakia and head and neck squamous cell carcinoma: a multicenter experimental study.

International journal of surgery (London, England)
BACKGROUND: Loss of chromosome 9p is an important biomarker in the malignant transformation of oral leukoplakia (OLK) to head and neck squamous cell carcinoma (HNSCC), and is associated with the prognosis of HNSCC patients. However, various challenge...

Artificial intelligence-based multi-modal multi-tasks analysis reveals tumor molecular heterogeneity, predicts preoperative lymph node metastasis and prognosis in papillary thyroid carcinoma: a retrospective study.

International journal of surgery (London, England)
BACKGROUND: Papillary thyroid carcinoma (PTC) is the predominant form of thyroid cancer globally, especially when lymph node metastasis (LNM) occurs. Molecular heterogeneity, driven by genetic alterations and tumor microenvironment components, contri...

Prediction of sepsis among patients with major trauma using artificial intelligence: a multicenter validated cohort study.

International journal of surgery (London, England)
BACKGROUND: Sepsis remains a significant challenge in patients with major trauma in the ICU. Early detection and treatment are crucial for improving outcomes and reducing mortality rates. Nonetheless, clinical tools for predicting sepsis among patien...

Implementing an AI algorithm in the clinical setting: a case study for the accuracy paradox.

European radiology
OBJECTIVES: We report our experience implementing an algorithm for the detection of large vessel occlusion (LVO) for suspected stroke in the emergency setting, including its performance, and offer an explanation as to why it was poorly received by ra...

Detection of focal cortical dysplasia: Development and multicentric evaluation of artificial intelligence models.

Epilepsia
OBJECTIVE: Focal cortical dysplasia (FCD) is a common cause of drug-resistant focal epilepsy but can be challenging to detect visually on magnetic resonance imaging. Three artificial intelligence models for automated FCD detection are publicly availa...

Validation of AI-driven measurements for hip morphology assessment.

European journal of radiology
RATIONALE AND OBJECTIVES: Accurate assessment of hip morphology is crucial for the diagnosis and management of hip pathologies. Traditional manual measurements are prone to mistakes and inter- and intra-reader variability. Artificial intelligence (AI...

Forecasting Pediatric Trauma Volumes: Insights From a Retrospective Study Using Machine Learning.

The Journal of surgical research
INTRODUCTION: Rising pediatric firearm-related fatalities in the United States strain Trauma Centers. Predicting trauma volume could improve resource management and preparedness, particularly if daily forecasts are achievable. The aim of the study is...