AIMC Topic: RNA, Messenger

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Reduced- and Full-Order Observers for Delayed Genetic Regulatory Networks.

IEEE transactions on cybernetics Jul 21, 2017
This paper is centered upon the state estimation for delayed genetic regulatory networks. Our aim is at estimating the concentrations of mRNAs and proteins by designing reduced-order and full-order state observers based on available network outputs. ...
RNA, Messenger Models, Statistical Neural Networks, Computer Algorithms Reproducibility of Results Gene Regulatory Networks
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Combining Supervised and Unsupervised Learning for Improved miRNA Target Prediction.

IEEE/ACM transactions on computational biology and bioinformatics Jul 13, 2017
MicroRNAs (miRNAs) are short non-coding RNAs which bind to mRNAs and regulate their expression. MiRNAs have been found to be associated with initiation and progression of many complex diseases. Investigating miRNAs and their targets can thus help dev...
Gene Expression Profiling Transcriptome Support Vector Machine MicroRNAs Unsupervised Machine Learning Supervised Machine Learning Gene Regulatory Networks Computational Biology RNA, Messenger Sequence Analysis, RNA
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Identifying N-methyladenosine sites using multi-interval nucleotide pair position specificity and support vector machine.

Scientific reports Apr 25, 2017
N6-methyladenosine (mA) refers to methylation of the adenosine nucleotide acid at the nitrogen-6 position. It plays an important role in a series of biological processes, such as splicing events, mRNA exporting, nascent mRNA synthesis, nuclear transl...
Support Vector Machine Humans Nucleotides Algorithms Saccharomyces cerevisiae Datasets as Topic Computational Biology Adenosine RNA, Messenger Arabidopsis
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Identification of miRNA-mRNA Modules in Colorectal Cancer Using Rough Hypercuboid Based Supervised Clustering.

Scientific reports Feb 21, 2017
Differences in the expression profiles of miRNAs and mRNAs have been reported in colorectal cancer. Nevertheless, information on important miRNA-mRNA regulatory modules in colorectal cancer is still lacking. In this regard, this study presents an app...
Humans Prognosis RNA, Messenger Support Vector Machine Databases, Genetic Cluster Analysis Colorectal Neoplasms Transcriptome Gene Regulatory Networks MicroRNAs Up-Regulation Kaplan-Meier Estimate
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Identification of Factors for the Preoperative Prediction of Tumour Subtype and Prognosis in Patients with T1 Lung Adenocarcinoma.

Disease markers Dec 26, 2016
Identification of factors that can predict the subtypes of lung adenocarcinoma preoperatively is important for selecting the appropriate surgical procedure and for predicting postoperative survival. We retrospectively evaluated 87 patients with lun...
Adult Carcinoembryonic Antigen Survival Rate Lung Neoplasms Humans Biomarkers, Tumor Preoperative Care RNA, Messenger Male Middle Aged Prognosis Adenocarcinoma Female Neoplasm Invasiveness Real-Time Polymerase Chain Reaction Follow-Up Studies Aged Reverse Transcriptase Polymerase Chain Reaction Retrospective Studies MicroRNAs Aged, 80 and over Tomography, X-Ray Computed Neoplasm Staging
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Genome-Wide Transcriptional and Post-transcriptional Regulation of Innate Immune and Defense Responses of Bovine Mammary Gland to .

Frontiers in cellular and infection microbiology Dec 26, 2016
() is problematic for lactating mammals and public health. Understanding of mechanisms by which the hosts respond to severe invasion of remains elusive. In this study, the genome-wide expression of mRNAs and miRNAs in bovine mammary gland cells wer...
Gene Expression Profiling Cattle RNA, Messenger Immunity, Innate MicroRNAs Staphylococcal Infections Mastitis, Bovine Humans Animals Mammary Glands, Human
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Identification of DEP domain-containing proteins by a machine learning method and experimental analysis of their expression in human HCC tissues.

Scientific reports Dec 21, 2016
The Dishevelled/EGL-10/Pleckstrin (DEP) domain-containing (DEPDC) proteins have seven members. However, whether this superfamily can be distinguished from other proteins based only on the amino acid sequences, remains unknown. Here, we describe a com...
GTPase-Activating Proteins Dishevelled Proteins Cluster Analysis Protein Domains Amino Acid Motifs Real-Time Polymerase Chain Reaction Liver Neoplasms Carcinoma, Hepatocellular Computational Biology RNA, Messenger Gene Expression Regulation, Neoplastic Machine Learning Signal Transduction Algorithms Phylogeny Humans Gene Expression Profiling
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MiRNATIP: a SOM-based miRNA-target interactions predictor.

BMC bioinformatics Sep 22, 2016
BACKGROUND: MicroRNAs (miRNAs) are small non-coding RNA sequences with regulatory functions to post-transcriptional level for several biological processes, such as cell disease progression and metastasis. MiRNAs interact with target messenger RNA (mR...
MicroRNAs Binding Sites Algorithms Humans Caenorhabditis elegans Animals Artificial Intelligence Computational Biology Software RNA, Messenger
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GOexpress: an R/Bioconductor package for the identification and visualisation of robust gene ontology signatures through supervised learning of gene expression data.

BMC bioinformatics Mar 11, 2016
BACKGROUND: Identification of gene expression profiles that differentiate experimental groups is critical for discovery and analysis of key molecular pathways and also for selection of robust diagnostic or prognostic biomarkers. While integration of ...
Supervised Machine Learning Gene Ontology Software Transcriptome Computational Biology RNA, Messenger
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Anethole improves the in vitro development of isolated caprine secondary follicles.

Theriogenology Dec 28, 2015
The aim of this study was to investigate the effect of three concentrations of anethole (30, 300, and 2000 μg/mL) on survival, antrum formation, follicular diameter, and oocyte maturation in the caprine species. The study also evaluated the effects o...
In Vitro Oocyte Maturation Techniques Allylbenzene Derivatives Anisoles RNA, Messenger Female Reactive Oxygen Species Animals Goats Ovarian Follicle
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