Epstein-Barr virus (EBV) associated gastric cancer, accounting for ~ 9% of all gastric cancers, has unique pathologic, genomic, and clinical features and is linked to a better prognosis. Therefore, we aim to develop and validate a robust deep learnin...
Chronic kidney disease (CKD) can induce chronic heart failure (CHF), a condition referred to as type 4 cardiorenal syndrome (CRS4). The pathophysiological mechanisms remain unclear, and suitable early warning biomarkers for CHF in CKD patients are la...
BACKGROUND: Vascular mild cognitive impairment (VMCI) is a significant global health concern, particularly in Asia. The visual cognitive assessment test (VCAT) has shown promise as a language-neutral screening tool for cognitive impairment.
INTRODUCTION: Intradialytic hypotension (IDH) remains a prevalent complication of hemodialysis, which is associated with adverse outcomes for patients. This study seeks to harness machine learning to construct predictive models for IDH based on multi...
BACKGROUND: Glaucoma is a progressive neurodegenerative disease of the optic nerve and one of the leading causes of irreversible blindness worldwide. Small RNAs (including miRNAs) play an important role in the pathogenesis of the disease. Despite ext...
OBJECTIVE: Posthepatectomy recurrence of hepatocellular carcinoma (HCC) is a major cause of poor prognosis. Accurate prediction is essential for reducing the burden of advanced disease and improving outcomes.
BACKGROUND: CST4 is associated with various cancers but its diagnostic value in colorectal cancer (CRC) has not been clearly established. This study aims to further validate the diagnostic value of CST4 in colorectal cancer using random forest models...
BACKGROUND AND OBJECTIVES: Hematologic toxicity (HT) is a common and serious side effect for advanced cervical cancer patients undergoing chemoradiotherapy. Accurately predicting HT can significantly improve patient management and treatment outcomes....
BACKGROUND: Preeclampsia (PE) is a serious hypertensive complication during pregnancy characterized by immune dysregulation and vascular dysfunction, however, the precise molecular mechanisms and effective therapeutic strategies remain unclear. This ...
International journal of colorectal disease
Sep 26, 2025
OBJECTIVE: In this study, we constructed a new pCR predictor based on dynamic tumor marker changes before and after NCRT, the dynamic tumor marker score (DTMS), and combined it with other clinicopathological features to build a machine-learning model...
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