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Predicting essential genes of 41 prokaryotes by a semi-supervised method.

Analytical biochemistry
Essential genes are vitally important to the survival and reproduction of organisms. Many machine learning methods have been widely employed to predict essential genes and have obtained satisfactory results. However, most of these methods are supervi...

Using Machine Learning to Make Predictions in Patients Who Fall.

The Journal of surgical research
BACKGROUND: As the population ages, the incidence of traumatic falls has been increasing. We hypothesize that a machine learning algorithm can more accurately predict mortality after a fall compared with a standard logistic regression (LR) model base...

Utilization of machine-learning models to accurately predict the risk for critical COVID-19.

Internal and emergency medicine
Among patients with Coronavirus disease (COVID-19), the ability to identify patients at risk for deterioration during their hospital stay is essential for effective patient allocation and management. To predict patient risk for critical COVID-19 base...

m7GPredictor: An improved machine learning-based model for predicting internal m7G modifications using sequence properties.

Analytical biochemistry
As one of the most important post-transcriptional modifications, the N7-methylguanosine (m7G) plays a key role in many RNA processing events. The accurate identification of m7G is crucial for elucidating its biological significance and future applica...

Deep Learning Modeling of Androgen Receptor Responses to Prostate Cancer Therapies.

International journal of molecular sciences
Gain-of-function mutations in human androgen receptor (AR) are among the major causes of drug resistance in prostate cancer (PCa). Identifying mutations that cause resistant phenotype is of critical importance for guiding treatment protocols, as well...

Time-series cardiovascular risk factors and receipt of screening for breast, cervical, and colon cancer: The Guideline Advantage.

PloS one
BACKGROUND: Cancer is the second leading cause of death in the United States. Cancer screenings can detect precancerous cells and allow for earlier diagnosis and treatment. Our purpose was to better understand risk factors for cancer screenings and a...

Machine Learning Prediction of Stroke Mechanism in Embolic Strokes of Undetermined Source.

Stroke
BACKGROUND AND PURPOSE: One-fifth of ischemic strokes are embolic strokes of undetermined source (ESUS). Their theoretical causes can be classified as cardioembolic versus noncardioembolic. This distinction has important implications, but the categor...

A Linear Regression and Deep Learning Approach for Detecting Reliable Genetic Alterations in Cancer Using DNA Methylation and Gene Expression Data.

Genes
DNA methylation change has been useful for cancer biomarker discovery, classification, and potential treatment development. So far, existing methods use either differentially methylated CpG sites or combined CpG sites, namely differentially methylate...

Comparing different deep learning architectures for classification of chest radiographs.

Scientific reports
Chest radiographs are among the most frequently acquired images in radiology and are often the subject of computer vision research. However, most of the models used to classify chest radiographs are derived from openly available deep neural networks,...

Development of a Deep Learning-Based Model for Diagnosing Breast Nodules With Ultrasound.

Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine
OBJECTIVES: Artificial intelligence (AI) has been an important addition to medicine. We aimed to explore the use of deep learning (DL) to distinguish benign from malignant lesions with breast ultrasound (BUS).